Evidence map›Paper›PMID 40350557›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025

Enhancing the Reliability of Cartilage Repair Evaluation: A Simplified Volume-Based Approach.

Jani Puhakka, Teemu Paatela, Eve Salonius, Virpi Muhonen, Anna Meller, Anna Vasara, Hannu Kautiainen, Jussi Kosola, Ilkka Kiviranta

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Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jani PuhakkaDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-1107-2531
Teemu PaatelaDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6389-051X
Eve SaloniusDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.
Virpi MuhonenDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.
Anna MellerLaboratory Animal Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Anna VasaraDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.
Hannu KautiainenPrimary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
Jussi KosolaDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.
Ilkka KivirantaDepartment of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland.

Funding

This study was supported by Tekes (No. 40171/14), Novo Nordisk Fonden (No. 17196), and Helsingin ja Uudenmaan Sairaanhoitopiiri (TYH2015207).
6 · The paper itself

Abstract

The purpose of this study was to explore methods for enhancing the reliability of arthroscopic cartilage repair evaluation. We compared a new volume-based scoring technique that assessed the extent of high-quality cartilage repair tissue in four quadrants of the repair tissue with the International Cartilage Repair Society (ICRS) score. Using a porcine cartilage repair model, we evaluated the inter- and intrarater reliability of the new volume-based technique. Nine defects were treated with a recombinant human Type III collagen/polylactide scaffold, whereas nine were left to heal spontaneously. The reliability of the volume-based score was analyzed using intraclass correlation coefficients (ICCs), and external validation was performed by comparing the score with histological ICRS II results. The volume-based score demonstrated moderate to good interrater reliability (ICC 0.67-0.78) and intrarater reliability (ICC 0.58-0.84), outperforming the ICRS score in consistency. Moderate positive correlations were observed between the volume-based score and histological ICRS II subscores (r

Indexed as

ArthroscopyCartilage, ArticularAnimalsReproducibility of ResultsSwineTissue Scaffoldsanimal modelarthroscopycartilage repairICRSpreclinicalreliabilityscoring system

Identifiers

PMID40350557
PMCPMC12258128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.