ArticleMicrobiome2025
Dietary selection of distinct gastrointestinal microorganisms drives fiber utilization dynamics in goats.
Article in Microbiome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Segment-Specific Gut Microbiome and Bile Acid Profiles in Grazing and Stall-Fed Yaks.Microorganisms · 2026Article
- Bioprocessing of mixed oil palm by-products with single and consortium white-rot fungi: Effects on nutritional quality, in vitro rumen fermentation, methane production, and rumen microbial populations.Veterinary world · 2026Article
- Soft-Pellet Feed Strategy for Broilers: Effects on Growth Performance and Liver-Intestinal Health.Animals : an open access journal from MDPI · 2026Article
- Nutritional Strategies for Methane, Nitrogen, and Phosphorus Mitigation in Ruminants: Mechanisms, Applications, and Regional Adaptations.Microorganisms · 2026Review
- AAnimals : an open access journal from MDPI · 2026Article
- Multi-omics analysis of soy isoflavone-induced responses in rumen fermentation, endocrine status and milk production in cows with varying milk yields.Journal of animal science and biotechnology · 2026Article
- Effects of L-Citrulline Supplementation on Rumen Microbiota and Reproductive Performance of Ewes.Life (Basel, Switzerland) · 2026Article
- Phytosterols improve feed efficiency in yaks by enriching rumen Succiniclasticum.Animal microbiome · 2026Article
- Characterization of Enterococcus faecalis JM263 from the Yak Gut on the Qinghai-Tibet Plateau: A Probiotic Candidate with Strong Fiber-Degrading Capacity.Probiotics and antimicrobial proteins · 2026Article
- Study on Differences in Lipid Composition of Camel Milk with Different Forage-to-Concentrate Diets.Animals : an open access journal from MDPI · 2026Article
- Effects of L-citrulline supplementation in the basal diet on reproductive performance, serum metabolites, and microbial community structure in Simmental cows.Frontiers in microbiology · 2026Article
- Microbiota-associated antioxidant responses to selenium source and probiotic supplementation in beef cattle.Frontiers in veterinary science · 2026Article
- Effects of compound Chinese herbal microecological preparations on growth performance, meat quality and rumen microflora of Simmental cattle.Frontiers in genetics · 2026Article
- Mechanisms and Applications of Gastrointestinal Microbiota-Metabolite Interactions in Ruminants: A Review.Microorganisms · 2025Review
- Spatial Multi-Omics Analysis of the Qianqiu Goat Gut Microbiome and Metabolome.International journal of molecular sciences · 2025Article
- Longitudinal hematological dynamics during pregnancy and lactation in Thuringian Forest dairy goats under organic farming conditions.Veterinary world · 2025Article
- Grazing versus housing in native dairy goats: Impacts on milk yield, composition, and conjugated linoleic acid enrichment under arid conditions.Veterinary world · 2025Article
- Joint Bacterial Traces in the Gut and Oral Cavity of Obesity Patients Provide Evidence for Saliva as a Rich Microbial Biomarker Source.Nutrients · 2025Article
- Influence of creatine pyruvate on newly received cattle: insights from metagenomics and metabolomics.BMC microbiology · 2025Article
- Metagenomics research on the gut microbiota of theBiosafety and health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary fiber is crucial to animal productivity and health, and its dynamic utilization process is shaped by the gastrointestinal microorganisms in ruminants. However, we lack a holistic understanding of the metabolic interactions and mediators of intestinal microbes under different fiber component interventions compared with that of their rumen counterparts. Here, we applied nutritional, amplicon, metagenomic, and metabolomic approaches to compare characteristic microbiome and metabolic strategies using goat models with fast-fermentation fiber (FF) and slow-fermentation fiber (SF) dietary interventions from a whole gastrointestinal perspective.
resultsThe SF diet selected fibrolytic bacteria Fibrobacter and Ruminococcus spp. and enriched for genes encoding for xylosidase, endoglucanase, and galactosidase in the rumen and cecum to enhance cellulose and hemicellulose utilization, which might be mediated by the enhanced microbial ATP production and cobalamin biosynthesis potentials in the rumen. The FF diet favors pectin-degrading bacteria Prevotella spp. and enriched for genes encoding for pectases (PL1, GH28, and CE8) to improve animal growth. Subsequent SCFA patterns and metabolic pathways unveiled the favor of acetate production in the rumen and butyrate production in the cecum for SF goats. Metagenomic binning verified this distinct selection of gastrointestinal microorganisms and metabolic pathways of different fiber types (fiber content and polysaccharide chemistry).
conclusionsThese findings provide novel insights into the key metabolic pathways and distinctive mechanisms through which dietary fiber types benefit the host animals from the whole gastrointestinal perspective. Video Abstract.
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