Evidence map›Paper›PMID 40350267›Full record

ArticleEndocrine journal2025

Impact of pre-pregnant body mass index and gestational weight gain on the development of hypertensive disorders of pregnancy: the KODMO study.

Yuka Matoba, Misato Ishikawa, Natsuo Tsutsumida, Kentaro Yamada, Naohiro Imazono, Kano Hayashi, Junki Abe, Kosuke Kawakami, Naofumi Ookura, Yoshihiro Ogawa

Abstract read
In one paragraph

Article in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuka MatobaDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.ORCID http://orcid.org/0009-0008-6867-1392
Misato IshikawaDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Natsuo TsutsumidaDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Kentaro YamadaDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Naohiro ImazonoDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Kano HayashiDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Junki AbeDepartment of Diabetes, Endocrinology and Metabolism, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Kosuke KawakamiDepartment of Obstetrics and Gynecology, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Naofumi OokuraDepartment of Obstetrics and Gynecology, NHO Kokura Medical Center, Kitakyushu 802-8533, Japan.
Yoshihiro OgawaDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obese pregnant women are more likely to develop hypertensive disorders of pregnancy (HDP), which puts them at risk for future cardiovascular events and type 2 diabetes. This study aimed to investigate the relationship between body weight and HDP in nondiabetic singleton-pregnant women. We examined the KODMO database, which included 5,120 pregnant women who gave birth at NHO Kokura Medical Center between January 2009 and December 2019, excluding those with pre-existing diabetes mellitus, hypertension, or multiple pregnancies. A multivariate logistic regression analysis of potential HDP risk factors revealed that both pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) were independent risk factors. The estimated impact was considerably greater in women with higher pre-pregnancy BMI, with odds ratios of 1.60 (95% CI: 1.18-2.18, p = 0.0025) for obesity degree 1 (25 ≤ BMI < 30 kg/m

Indexed as

Body Mass IndexGestational Weight GainHypertension, Pregnancy-InducedObesityAdultFemaleHumansJapanPregnancyRetrospective StudiesRisk FactorsGestational diabetes mellitus (GDM)Gestational weight gain (GWG)Hypertensive disorders of pregnancy (HDP)ObesityPre-pregnant body mass index (BMI)

Identifiers

PMID40350267
PMCPMC12340249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.