Evidence map›Paper›PMID 40349845›Full record

Observational studyClinical nutrition ESPEN2025

Vitamin B

Heather M Guetterman, Krista S Crider, Amy Fothergill, Beena Bose, Christina B Johnson, Shameem Jabbar, Mindy Zhang, Christine M Pfeiffer, Charles E Rose, Yan Ping Qi and 4 more

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Clinical nutrition ESPEN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04048330 (Periconceptional Surveillance for Prevention of Anemia and Birth Defects in India), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04048330 unknown statusnot on this map

Periconceptional Surveillance for Prevention of Anemia and Birth Defects in India

TypeobservationalSponsorCornell UniversityRan2018 to 2024Enrolled2,000ConditionsAnemia, Folate Deficiency, Vitamin B12 Deficiency
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Vitamin BThe Cochrane database of systematic reviews · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Heather M GuettermanDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Krista S CriderNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Amy FothergillDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Beena BoseSt. John's Research Institute, Bengaluru, Karnataka, India.
Christina B JohnsonArogyavaram Medical Centre, Andhra Pradesh, India.
Shameem JabbarNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mindy ZhangNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Christine M PfeifferNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Charles E RoseNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Yan Ping QiNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jennifer L WilliamsNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Saurabh MehtaDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA; St. John's Research Institute, Bengaluru, Karnataka, India; Cornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, Ithaca, NY, USA; Division of Epidemiology, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Rebecca KuriyanSt. John's Research Institute, Bengaluru, Karnataka, India.
Julia L FinkelsteinDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA; St. John's Research Institute, Bengaluru, Karnataka, India; Cornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, Ithaca, NY, USA; Division of Epidemiology, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA. Electronic address: jfinkelstein@cornell.edu.

Funding

NUTRITION TRAININGT32DK007158 · NIDDK · CORNELL UNIVERSITY ITHACA · PI PATRICIA A CASSANO, Julia L. Finkelstein · 1986 to 2026
$7.4M
TRAINING IN MATERNAL AND CHILD NUTRITIONT32HD087137 · NICHD · CORNELL UNIVERSITY · PI Laura Bellows, Julia L. Finkelstein · 2016 to 2026
$2.0M
NCBDD CDC HHS U01 DD001007NCBDD CDC HHS U19 DD001218NICHD NIH HHS T32 HD087137NIDDK NIH HHS T32 DK007158
6 · The paper itself

Abstract

BACKGROUND AND

aimsIn clinical populations, vitamin B

methodsParticipants (n = 980 women 15-40 y; not pregnant or lactating) were assessed for total vitamin B

resultsOverall, 25 % of participants had HbA1c ≥5.7 % (HbA1c ≥5.7-<6.5 %: 20.0 %; ≥6.5 %: 5.0 %), and 18.6 % had hypertension (Stage 1: 16.4 %; Stage 2: 2.2 %). Among adults, 23.4 % had body mass index of (BMI) 25.0-<30.0 kg/m

conclusionsThe burden of adverse metabolic characteristics was substantial in this population of young, apparently healthy women. Among those with vitamin B REGISTRATION NUMBER: NCT04048330.

Indexed as

Nutritional StatusVitamin B 12Vitamin B 12 DeficiencyAdiposityAdolescentAdultBiomarkersBody Mass IndexCross-Sectional StudiesFemaleGlycated HemoglobinHomocysteineHumansHypertensionIndiaMethylmalonic AcidBiomarkersGlycated HemoglobinHomocysteineMethylmalonic AcidVitamin B 12Body compositionMetabolic healthOverweightPericonceptionalVitamin B(12)

Identifiers

PMID40349845
PMCPMC12256199

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.