ArticleUrology2025
Effect of Age on Robotic-Assisted Radical Prostatectomy Outcomes: A Multi-center Analysis.
Article in Urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Age-stratified trajectories of patient-reported outcomes and perioperative safety after robot-assisted radical prostatectomy: a prospective multicenter cohort study.Scientific reports · 2026Article
- Increasing Age at Radical Prostatectomy: A Total Population Analysis in Germany from 2006 to 2022.Annals of surgical oncology · 2026Article
- Robotic-assisted radical prostatectomy in patients 80+ years: a multi-centre experience.Journal of robotic surgery · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo evaluate the association between age and risk of perioperative complications and whether age-related increases in complication risk are of clinical significance in the era of robotic-assisted radical prostatectomies.
methodsWe pooled prostatectomy outcomes during 2012-2022 from Cornell (n = 585), Georgetown (n = 319), and Memorial Sloan Kettering (n = 6419) to assess the primary outcome of any major complication (Clavien-Dindo grade ≥3) within 30 days of surgery. We used multivariable regression to determine the relationship between age and complications, adjusting for surgeon volume and oncologic risk (prostate specific antigen, surgery grade group, extracapsular extension, seminal vesical invasion, lymph node involvement, and surgical margin status).
resultsMajor complications were similar at 2.2%, 4.1%, and 2.1% for Cornell, Georgetown, and Memorial Sloan Kettering, respectively. Older age was associated with an increased risk of complications (OR 1.03 per year, 95% CI 1.00-1.05, P = .022). However, the absolute increase in risk was small; the estimated risk of major complication for a 60-, 70- and 80-year-old was 2.0% (95% CI 1.7-2.4), 2.6% (95% CI 2.1-3.2) and 3.3% (95% CI 2.2-4.9), respectively. Limitations include observational biases associated with the retrospective study design.
conclusionOur study is the first to demonstrate that although older age is associated with an increased risk of complications, the absolute increase in risk is low and excludes a clinically relevant increase in risk in older men. Therefore, the risk of complications alone should not drive treatment choice in well-selected older prostate cancer patients.
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Registered trials
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