Evidence map›Paper›PMID 40349161›Full record

Trial reportAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial.

Oliver J Perkin, Sophie E Davies, Martin Hewison, Kerry S Jones, Javier T Gonzalez, James A Betts, Carl Jenkinson, Mark A Lindsay, Sarah R Meadows, Damon A Parkington and 2 more

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Oliver J PerkinCentre for Nutrition and Exercise Metabolism, Department for Health, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0001-8921-8708
Sophie E DaviesCentre for Nutrition and Exercise Metabolism, Department for Health, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0002-6069-1056
Martin HewisonInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0001-5806-9690
Kerry S JonesNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SL, UK.ORCID https://orcid.org/0000-0002-7380-9797
Javier T GonzalezCentre for Nutrition and Exercise Metabolism, Department for Health, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0002-9939-0074
James A BettsCentre for Nutrition and Exercise Metabolism, Department for Health, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0002-9129-5777
Carl JenkinsonUniversity of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-1838-5282
Mark A LindsayDepartment of Life Sciences, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0003-4807-5506
Sarah R MeadowsNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SL, UK.ORCID https://orcid.org/0000-0001-5222-0257
Damon A ParkingtonNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SL, UK.ORCID https://orcid.org/0000-0001-5043-5377
Albert KoulmanNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SL, UK.ORCID https://orcid.org/0000-0001-9998-051X
Dylan ThompsonCentre for Nutrition and Exercise Metabolism, Department for Health, University of Bath, Bath, BA2 7AY, UK.ORCID https://orcid.org/0000-0002-6312-1518

Funding

Biotechnology and Biological Sciences Research Council BB/R018928/1NIHR Cambridge Biomedical Research Centre NIHR203312Wellcome TrustWellcome Trust 203141/A/16/Z
6 · The paper itself

Abstract

Many adults become vitamin D deficient or insufficient during winter at northerly latitudes when cutaneous vitamin D synthesis does not occur. Vitamin D accumulates in adipose tissue and people with overweight or obesity are more likely to have low systemic vitamin D. This randomized controlled trial demonstrates that regular exercise completely maintains serum concentrations of the active vitamin D metabolite 1,25(OH)

Indexed as

ExerciseVitamin DVitamin D DeficiencyAdultDietary SupplementsFemaleHumansMaleMiddle AgedObesityOverweightSeasonsWeight LossVitamin D1,25(OH)DExerciseVitaDExVitamin DWeight StableWinter

Identifiers

PMID40349161
PMCPMC12165100

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.