Evidence map›Paper›PMID 40349026›Full record

ArticleBMC pulmonary medicine2025

Physician perspectives on pulmonary hypertension in ILD: results of a cases-based survey.

Ho Cheol Kim, Christopher S King, Christopher Thomas, Vikramjit Khangoora, Osman Malik, Jared Wilkinson, Shambhu Aryal, Anju Singhal, Alan Nyquist, Oksana A Shlobin and 1 more

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ho Cheol KimDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Christopher S KingAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Christopher ThomasAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Vikramjit KhangooraAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Osman MalikAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Jared WilkinsonAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Shambhu AryalAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Anju SinghalAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Alan NyquistAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Oksana A ShlobinAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA.
Steven D NathanAdvanced Lung Disease and Transplant Program, Inova Schar Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA, USA. Steven.nathan@inova.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary hypertension (PH) complicates the course of patients with interstitial lung disease (ILD) in 30-55% of cases and is associated with increased morbidity and mortality. The optimal timing of diagnostic right heart catheterization (RHC) and the impact of transthoracic echocardiographic (TTE) imaging on this decision remain uncertain. This study explores physician decision-making regarding PH suspicion in patients with ILD, and the necessity for TTE and RHC.

methodsA case-based survey was conducted among physicians from diverse geographic and professional backgrounds. Participants assessed anonymized ILD cases, providing their clinical suspicion of PH and recommendations for TTE and then RHC both before and after receiving TTE results. Predictive accuracy for PH was compared to the FORD index, a validated scoring system.

resultsThere were 10 cases provided, of which 3 had hemodynamically confirmed PH and 7 did not have PH. There were 42 respondents to the survey. Following the TTE results, the proportion of responses indicating high suspicion for PH increased in all PH cases and also increased in some non-PH cases. In PH cases, respondents accurately predicted mPAP ≥ 25 in 98.4% and PVR ≥ 3 Woods Units in 90.5% of responses, although only 24.6% and 20.6% matched the value ranges, respectively. In non-PH cases, mPAP < 25 and PVR < 3 Wood Units were correctly identified in 60.9% and 67.0% of responses, with 30% incorrectly predicting PH. Compared to the FORD index (sensitivity: 43.7%, specificity: 86.6%), respondents demonstrated higher sensitivity (88.9%) but lower specificity (70.1%) for PH diagnosis.

conclusionsPhysicians demonstrate high sensitivity but moderate specificity in predicting PH, both with and without TTE results. The FORD index had greater specificity and may serve as a complementary tool, reducing the need for unnecessary RHCs. Standardized protocols are needed to facilitate detection of PH while optimizing the timing of RHCs in ILD patients.

Indexed as

Clinical Decision-MakingHypertension, PulmonaryLung Diseases, InterstitialPhysiciansAgedCardiac CatheterizationEchocardiographyFemaleHumansMaleMiddle AgedSurveys and QuestionnairesInterstitial lung diseasePulmonary hypertensionSurvey

Identifiers

PMID40349026
PMCPMC12066071

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.