Evidence map›Paper›PMID 40349009›Full record

ArticleBMC public health2025

Indirect costs constitute a major part of the total economic burden of obesity: a Finnish population-based cohort study.

Aino Vesikansa, Juha Mehtälä, Susanna Aspholm, Kirsi Kallio-Grönroos, Katja Mutanen, Annamari Lundqvist, Tiina Laatikainen, Tero Saukkonen, Kirsi H Pietiläinen

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aino VesikansaMedEngine Oy, Eteläranta 14, 00100, Helsinki, Finland.
Juha MehtäläMedEngine Oy, Eteläranta 14, 00100, Helsinki, Finland. juha.mehtala@medengine.fi.
Susanna AspholmNovo Nordisk Farma Oy, Espoo, Finland.
Kirsi Kallio-GrönroosNovo Nordisk Farma Oy, Espoo, Finland.
Katja MutanenNovo Nordisk Farma Oy, Espoo, Finland.
Annamari LundqvistFinnish Institute for Health and Welfare, Helsinki, Finland.
Tiina LaatikainenFinnish Institute for Health and Welfare, Helsinki, Finland.
Tero SaukkonenNovo Nordisk Farma Oy, Espoo, Finland.
Kirsi H PietiläinenObesity Research Unit, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe growing prevalence of overweight and obesity (OB) poses a considerable economic burden worldwide. However, nationally representative, detailed analyses estimating the total burden of OB are few. We characterized direct, indirect, and total costs of overweight and obesity in a population-based cohort of Finnish adult individuals and evaluated the additional total costs attributed to overweight and obesity.

methodsThe study cohort included 5,587 randomly-selected individuals (≥18 years of age) who participated in the national FinHealth 2017 health examination survey. The main study group consisted of working-age individuals (18-64 years of age; n = 3,914). Individual-level data were collected from the nationwide registers by the Finnish Institute for Health and Welfare (healthcare resource utilization), Social Insurance Institution of Finland (prescription medications, sick leaves, disability pensions, rehabilitation periods), and Statistics Finland (deaths). Indirect costs were calculated using the Human Capital Approach, and direct costs were based on the medication purchases and healthcare resource use.

resultsThe mean annual indirect costs were €1,683 (SD, €6,395) per person for the working-age individuals with normal-weight (NW), €2,957 (€8,797) for individuals with overweight (OW), €4,488 (€11,607) for individuals with class I obesity (OBI), and €4,654 (€11,383) for individuals with class II-III obesity (OBII-III). The mean annual total (direct + indirect) costs were €3,314 (SD, €8,358) per person in the NW, €4,902 (€10,747) in the OW, €7,129 (€14,313) in the OBI, and €7,372 (€14,423) in the OBII-III groups. Compared with individuals with NW, OW was associated with 31% (rate ratio, RR, 1.31; 95% CI, 1.09-1.58; p = 0.005), OBI with 83% (RR, 1.83; 95% CI, 1.46-2.28; p < 0.001), and OBII-III with 95% (RR, 1.95; 95% CI, 1.48-2.55; p < 0.001) higher total costs in working-age individuals. When adjusted for age and sex, the predicted total annual cost difference per person was €1,124 for OW, €3,002 for OBI, and €3,443 for OBII-III compared with a person with NW.

conclusionsIndirect costs constitute a major part of the total costs of obesity in the working-age population. Compared with NW, the total costs are significantly higher not only for severe obesity, but also for OW and OBI.

Indexed as

Cost of IllnessHealth Care CostsObesityAdolescentAdultCohort StudiesFemaleFinlandHealth SurveysHumansMaleMiddle AgedYoung AdultBody-mass indexDirect costsEconomic burdenIndirect costsObesityTotal costs

Identifiers

PMID40349009
PMCPMC12065301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.