Evidence map›Paper›PMID 40348940›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2025

Diagnostic and therapeutic precision in cardiovascular diseases in the neonatal intensive care.

Arvind Sehgal, Matthew R Buckingham, Rachael M Hyland, Patrick J McNamara

Abstract readReview
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arvind Sehgal *Monash Children's Hospital, Monash University, Melbourne, VIC, Australia. Arvind.Sehgal@monash.edu.ORCID http://orcid.org/0000-0003-2600-7529
Matthew R Buckingham *Waitaha Christchurch Neonatal Unit, The Whatu Ora Health, Christchurch, New Zealand.
Rachael M Hyland *Department of Pediatrics, University of Iowa, Iowa City, IA, USA.ORCID http://orcid.org/0000-0002-0605-3010
Patrick J McNamaraDepartment of Pediatrics, University of Iowa, Iowa City, IA, USA.ORCID http://orcid.org/0000-0001-7648-8872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While patent ductus arteriosus, pulmonary hypertension, and systemic hypotension are key medical issues amongst neonates, there are other common biological conditions which present with distinct physiological diagnostic and therapeutic challenges. This review focuses on such hemodynamic considerations in cardiomyopathy accompanying infants of diabetic mothers, twin-to-twin transfusion syndrome, and left heart pathology in infants with severe chronic lung disease. It details the pathophysiological mechanisms, diagnostic approaches, and therapeutic strategies essential for optimizing cardiovascular stability in this fragile cohort. A regimented, protocol-driven approach may lead to an increased risk of unintended treatment side effects in patients where diagnostic precision is low. This review provides a rational basis of the management of hemodynamic instability, at the same time laying out knowledge gaps and considerations for future research.

Indexed as

CardiomyopathiesCardiovascular DiseasesFetofetal TransfusionIntensive Care, NeonatalFemaleHemodynamicsHumansInfant, NewbornIntensive Care Units, NeonatalPregnancy

Identifiers

PMID40348940
PMCPMC12316595

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.