Evidence map›Paper›PMID 40348916›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Aqueductal glioma surgery via a telovelar approach using sodium fluorescein in a 6-year-old pediatric patient.

Sergio Cavalheiro, José Antonio Rangel Quiróz, Patricia Alessandra Dastoli, Isaque Hyung Tong Kim, Fernando Seiji Suzuki, Marcos Devanir Silva da Costa

Abstract readCase ReportsReview
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In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Surgical Approaches for Brainstem Tumors in Pediatric Patients.Advances and technical standards in neurosurgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sergio CavalheiroDepartment of Neurology and Neurosurgery, University Federal of São Paulo, São Paulo, Brazil.
José Antonio Rangel QuirózFellows of Pediatric Neurosurgery, Department of Neurology and Neurosurgery, University Federal of São Paulo, Rua Dos Otonis, Vila Clementino, 431, 2 Nd Floor, São Paulo, SP, 04025 - 001, Brazil. neurocirugiarangelch@gmail.com.
Patricia Alessandra DastoliDepartment of Neurology and Neurosurgery, University Federal of São Paulo, São Paulo, Brazil.
Isaque Hyung Tong KimFellows of Pediatric Neurosurgery, Department of Neurology and Neurosurgery, University Federal of São Paulo, Rua Dos Otonis, Vila Clementino, 431, 2 Nd Floor, São Paulo, SP, 04025 - 001, Brazil.
Fernando Seiji SuzukiDepartment of Neurology and Neurosurgery, University Federal of São Paulo, São Paulo, Brazil.
Marcos Devanir Silva da CostaDepartment of Neurology and Neurosurgery, University Federal of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periaqueductal gliomas are a subset of brainstem gliomas that typically present symptoms related to hydrocephalus due to obstruction of cerebrospinal fluid pathways. These tumors are generally low grade and have a favorable prognosis. Management often focuses on resolving hydrocephalus, with surgical intervention considered when symptoms or radiological images worsen. Sodium fluorescein is a fluorescent dye used in brain tumor surgeries to enhance visualization, allowing surgeons to distinguish between tumor tissue and normal brain tissue more effectively. This technique improves the precision and safety of tumor resection. We present the case of a 6-year-old patient in whom we performed the telovelar approach to resect periaqueductal gliomas via sodium fluorescein (2.5 mg/kg) for adequate resection, with excellent postoperative results. Ethics committee approval was not required to perform the surgical procedure on the patient. The patient's parents provided informed consent for the surgery and gave verbal consent for the publication of their video surgery.

Indexed as

Brain Stem NeoplasmsCerebral AqueductFluoresceinGliomaNeurosurgical ProceduresChildFluorescent DyesHumansHydrocephalusMaleFluoresceinFluorescent DyesChildrenFluorescentMidbrainTumor

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.