Evidence map›Paper›PMID 40348910›Full record

ArticleNPJ digital medicine2025

Digital measures of activity and motivation impact depression and anxiety in the real world.

Jacqueline M Beltrán, Yael Jacob, Marishka M Mehta, Tasnim Hossain, Abigail Adams, Samantha Fontaine, John Torous, Catherine McDonough, Matthew Johnson, Andrew D Delgado and 2 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacqueline M BeltránDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6311-9947
Yael JacobDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Marishka M MehtaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-5105-6723
Tasnim HossainDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Abigail AdamsDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samantha FontaineDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
John TorousBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5362-7937
Catherine McDonoughDepartment of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Matthew JohnsonThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrew D DelgadoDepartment of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
James W MurroughDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6286-1242
Laurel S MorrisDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Laurel.morris@mssm.edu.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
NCATS NIH HHS UL1 TR004419U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR004419U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) K01MH12043
6 · The paper itself

Abstract

Mood and anxiety disorders are highly comorbid, with symptom severity varying over time. Individuals with and without these disorders completed 30-days of ecological momentary assessment (EMAs) of depression, anxiety and distress, developed based on the established Mood and Anxiety Symptom Questionnaire (MASQ). These electronic MASQ (eMASQ) EMAs were collected alongside novel intrinsic and extrinsic motivation EMAs, and physical/digital activity measures (steps/screentime) across N = 70-101 participants. Each eMASQ-EMA significantly related to its corresponding MASQ measure. Extrinsic and intrinsic motivation negatively related to each eMASQ-EMA and had the greatest influence on patients' overall symptom profile. Physical, but not digital activity, was negatively associated with concurrent and 1-week lagged anxiety and depression, highlighting the temporally delayed benefits of physical activity on depression and anxiety symptoms in psychiatric groups. Collectively, this study suggests cognitive constructs related to drive and physical activity, may be useful in predicting continuous and transient psychiatric symptoms in the real-world.

Identifiers

PMID40348910
PMCPMC12065807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.