Trial reportScientific reports2025
Physiological adjustment effects of viewing natural environment images on heart rate variability in individuals with depressive and anxiety disorders.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Personality and spatial familiarity interact to shape affective responses in urban parks: a VR study.Frontiers in psychology · 2026Article
- Heart-focused breathing technique and attitude breathing technique effects on heart rate variability in young healthy subjects.Physiological reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Nature-based interventions improve mood and reduce stress, but their effects on heart rate variability (HRV) remain inconsistent. The physiological adjustment effect theory proposes HRV adjusts to an optimal value during nature contact-increasing when baseline HRV is low and decreasing when high. This study tested this theory in patients with depressive and anxiety disorders and investigated its association with mood changes. A randomized crossover trial was conducted with 60 patients. We assessed the correlation between baseline HRV during control images and HRV change after 3 min natural image viewing. We also examined mood changes in comfort, relaxation, and vigor. A significant negative correlation was found between baseline low-frequency/high-frequency (LF/HF) ratio and changes after viewing natural images, indicating a physiological adjustment effect in sympathetic activity. No significant correlation was found with the parasympathetic indicator, HF. Participants with adjustment effects in LF/HF had greater improvement in vigor. Those without these effects had higher alcohol use and tended towards more comorbid hypertension. Natural interventions may enhance vigor through physiological adjustment in sympathetic activity. The lack of adjustment effects is linked to behaviors and conditions associated with autonomic dysfunction, highlighting the need for targeted therapies in depressive and anxiety disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.