Evidence map›Paper›PMID 40348806›Full record

ArticleScientific reports2025

The synergistic anti-leishmanial effect of photodynamic therapy employing chemotherapy-mediated nanocomposites.

Elahe Molaakbari, Ahmad Khosravi, Ehsan Salarkia, Iraj Sharifi, Alireza Keyhani, Mehdi Bamorovat, Mohammad Zarif, Fatemeh Sharifi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Photodynamic Therapy in Dermatology.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elahe MolaakbariLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Ahmad KhosraviLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran. khosraviam@yahoo.com.
Ehsan SalarkiaLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Iraj SharifiLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Alireza KeyhaniLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Mehdi BamorovatLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad ZarifLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Fatemeh SharifiResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran.

Funding

Kerman University of Medical Sciences 99000897
6 · The paper itself

Abstract

Cutaneous leishmaniasis (CL) presents a significant therapeutic challenge due to limitations of current treatments like meglumine antimoniate (MAT), including drug resistance and adverse side effects. Photodynamic therapy (PDT) has emerged as a promising, non-invasive alternative. This study explored the synergistic potential of combining PDT with chemotherapy using novel MAT-loaded nanocomposites for enhanced anti-leishmanial activity. A novel nanocomposite, Co-Fe

Indexed as

Antiprotozoal AgentsLeishmaniasis, CutaneousLeishmania tropicaMeglumine AntimoniateNanocompositesPhotochemotherapyAnimalsHumansPhotosensitizing AgentsReactive Oxygen SpeciesAntiprotozoal AgentsMeglumine AntimoniatePhotosensitizing AgentsReactive Oxygen SpeciesAmphotricine BLeishmania tropicaMeglumine antimoniatePhotodynamic therapyPhotosentesizer Co-Fe2O4@GO-poly (AMPS-co-AM) nanocomposite

Identifiers

PMID40348806
PMCPMC12065788

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.