Evidence map›Paper›PMID 40348265›Full record

ArticleEnvironmental research2025

Linking soil-metal concentrations with children's blood and urine biomarkers in Syracuse, NY.

Dustin T Hill, Michael Petroni, Vikrant Jandev, Kestutis Bendinskas, Lynn S Brann, James A MacKenzie, Christopher D Palmer, Patrick J Parsons, Mary B Collins, Brooks B Gump

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dustin T HillFalk College of Sport and Human Dynamics, Department of Public Health, Syracuse University, Syracuse, NY, 13244, USA. Electronic address: dthill@syr.edu.
Michael PetroniDepartment of Environmental Science, SUNY College of Environmental Science and Forestry, Syracuse, NY, 13210, USA.
Vikrant JandevDepartment of Chemistry, State University of New York College at Oswego, Oswego, NY, 13126, USA.
Kestutis BendinskasDepartment of Chemistry, State University of New York College at Oswego, Oswego, NY, 13126, USA.
Lynn S BrannDepartment of Nutrition, Syracuse University, Syracuse, NY, 13244, USA.
James A MacKenzieDepartment of Biological Sciences, State University of New York College at Oswego, Oswego, NY, 13126, USA.
Christopher D PalmerLaboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, 12237, USA; Department of Environmental Health Sciences, College of Integrated Health Sciences, University at Albany, Rensselaer, NY, 12144, USA.
Patrick J ParsonsLaboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, 12237, USA; Department of Environmental Health Sciences, College of Integrated Health Sciences, University at Albany, Rensselaer, NY, 12144, USA.
Mary B CollinsSchool of Marine and Atmospheric Sciences, Sustainability Studies Division, Stony Brook University, Stony Brook, NY, USA; Institute for Advanced Computational Science, Stony Brook University, Stony Brook, NY, USA.
Brooks B GumpFalk College of Sport and Human Dynamics, Department of Public Health, Syracuse University, Syracuse, NY, 13244, USA.

Funding

Environmental Toxicants, Race, and Cardiovascular Disease Risk in ChildrenR01ES023252 · NIEHS · SYRACUSE UNIVERSITY · PI GUMP, BROOKS B. · 2013 to 2016
$1.9M
NIEHS NIH HHS R01 ES023252
6 · The paper itself

Abstract

This study investigates the relationship between trace element concentrations of lead (Pb), arsenic (As), cobalt (Co), manganese (Mn), molybdenum (Mo), and mercury (Hg) in soil on blood and urine biomarkers in a cohort of children from Syracuse, New York. The cohort data were collected as part of the Environmental Exposures and Child Health Outcomes project investigating the body burden of trace metals in children and where those metals come from. This study specifically investigates exposure to trace metals in soil. Cohort data were collected between 2013 and 2017 and soil samples were obtained from a separate study conducted in 2003-2004. We used linear and spatial-error models to test if daily dose exposure to soil concentrations of trace metals were associated with blood and urine levels of those same metals. We controlled for race, gender, socioeconomic status (index calculated from income and parent education level), age, body mass index, diet (index of daily dietary patterns of different food groups), smoking status of parents, distance to nearest highway, and air concentration of metal pollution. We found that a one standard deviation increase in soil-Pb may be associated with a 12 percent (95 % CI [2.5 %, 21 %]), rise in blood-Pb, and a one standard deviation increase in nearby soil-Hg levels may be associated with a 22.5 percent (90 % CI [1 %-49 %]) rise in blood-Hg. On average, participants had 2.5 μg/dL (95 % CI [1.6 μg/dL, 3.4 μg/dL]) higher blood-Pb levels for every 1000 mg/kg of soil-Pb. Participants also had 1.5 μg/g (95 % CI [0.78 μg/g, 2.2 μg/g]) creatinine higher adjusted urine-Co levels for every 1 μg/kg/day of soil-Co exposure with 10 percent variance explained by soil-Co dose (R

Indexed as

Environmental ExposureMetals, HeavySoil PollutantsAdolescentBiomarkersChildChild, PreschoolCohort StudiesEnvironmental MonitoringFemaleHumansMaleNew YorkSoilBiomarkersMetals, HeavySoilSoil PollutantsBlood leadChildrenEnvironmental healthExposomeSoil-metalsUrine metal biomarker

Identifiers

PMID40348265
PMCPMC13193073

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.