Evidence map›Paper›PMID 40347903›Full record

ArticleInternational journal of surgery case reports2025

Advancing pediatric genital reconstruction in a resource-limited setting: A case of subtunical reduction clitoroplasty in a young girl.

Mathayo Shadrack, Mohammed Sultan Salim, Petronilla Ngiloi, Zaituni Bokhary, Victor Ngotta, Abdulrahman Alshafei

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mathayo ShadrackMuhimbili University of Health and Allied Science (MUHAS), P.O. box 65001, Dar es salaam, Tanzania; Department of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania; Department of Pediatric Surgery, Kilimanjaro Christian Medical Center, P.O. Box 3010, Moshi, Kilimanjaro, Tanzania; Kilimanjaro Christian Medical University, P.O. Box 2240, Moshi, Kilimanjaro, Tanzania. Electronic address: shadrackmathew@gmail.com.
Mohammed Sultan SalimMuhimbili University of Health and Allied Science (MUHAS), P.O. box 65001, Dar es salaam, Tanzania; Department of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania.
Petronilla NgiloiMuhimbili University of Health and Allied Science (MUHAS), P.O. box 65001, Dar es salaam, Tanzania; Department of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania.
Zaituni BokharyMuhimbili University of Health and Allied Science (MUHAS), P.O. box 65001, Dar es salaam, Tanzania; Department of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania.
Victor NgottaMuhimbili University of Health and Allied Science (MUHAS), P.O. box 65001, Dar es salaam, Tanzania; Department of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania.
Abdulrahman AlshafeiDepartment of pediatric Surgery, Muhimbili National Hospital (MNH), P.O. Box 65000, Dar es salaam, Tanzania; Royal Medical Services, P.O.Box 28743, Riffa, Bahrain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital anomalies, including clitoromegaly, are significant challenges, particularly in resource-limited settings where access to specialized care may be lacking. Clitoral enlargement is often associated with disorders of sexual differentiation, such as congenital adrenal hyperplasia. Managing such conditions in under-resourced environments requires specialized surgical expertise and collaborative approach. CASE PRESENTATION: A 3-year-old girl from a resource-limited community was referred for management of clitoromegaly diagnosed since birth. Hormonal assays showed slightly elevated 17-hydroxyprogesterone, suggesting congenital adrenal hyperplasia with a 46XX karyotype. A diagnostic laparoscopy was performed, confirming normal female internal structures. Her parents were concerned about psychological implications. Subtunical clitoroplasty, an advanced reconstructive procedure preserving neurovascular function with labial reconstruction and vaginoplasty were recommended by visiting pediatric surgeons to restore a more typical anatomical appearance. DISCUSSION: The subtunical clitoroplasty was successfully performed, achieving favorable aesthetic and functional outcomes. The involvement of global health surgeons from a developed country facilitated the application of advanced techniques despite local resource constraints. This case emphasizes the value of global health collaborations in providing high-quality care in resource-limited settings. Ethical considerations, including the child's future autonomy and the psychological impact of surgery, were carefully addressed with the family.

conclusionThis case highlights the successful surgical management of clitoromegaly in a child from a resource-limited setting through subtunical clitoroplasty. It underscores the importance of international collaboration in advancing pediatric genital reconstruction and the need for ongoing support for both medical and psychosocial outcomes in such cases. Further research is needed to evaluate long-term outcomes in similar settings.

Indexed as

Ambiguous genitaliaClitoromegalyDisorders of sexual differentiation (DSDs)Pediatric genital reconstructionResource-limited settingSubtunical Clitoroplasty

Identifiers

PMID40347903
PMCPMC12139512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.