Evidence map›Paper›PMID 40347444›Full record

ArticlePsycho-oncology2025

'Finding Comfort in Discomfort': A Qualitative Study of Cancer Clinicians and Researchers' Experiences of Conducting a Cancer Rapid Autopsy Program.

Erin Tutty, Philomena Horsley, Rowan Forbes Shepherd, Laura Forrest

Abstract read
In one paragraph

Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erin TuttyParkville Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia.
Philomena HorsleyParkville Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia.
Rowan Forbes ShepherdParkville Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia.
Laura ForrestParkville Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia.ORCID 0000-0002-1126-4971

Funding

Donald Ratcliff and Phyllis MacLeod TrustPeter MacCallum Foundation
6 · The paper itself

Abstract

backgroundRapid autopsy offers a tantalising opportunity to better characterise metastatic disease and determine how malignancies evade treatment. The CASCADE (CAncer tiSsue Collection After DEath) rapid autopsy program at the Peter MacCallum Cancer Centre, established in 2012, has conducted more than 100 autopsies. The experiences of clinicians and researchers who conduct this program can offer insight into how a unique program can be conducted sensitively and how their involvement impacts them personally and professionally. PURPOSE: To explore experiences of the clinicians and researchers involved in the CASCADE cancer rapid autopsy program. MATERIALS AND

methodsA qualitative approach employing semi-structured interviews was used to collect data from clinicians and researchers working at the Peter MacCallum Cancer Centre. Inductive thematic analysis with team-based codebook development was used to generate findings.

resultsParticipants (N = 20) described the benefits and burdens of involvement in a cancer rapid autopsy program, including strategies used to 'find comfort in discomfort'. Offering participation in CASCADE enhanced patient-clinician rapport. The goals of the CASCADE program helped participants overcome confronting experiences in the autopsy room and use of autopsy-derived tissue in the laboratory. Peer-support is essential to avoid burnout.

conclusionThe benefits outweighed the burdens of delivering a cancer rapid autopsy program, however, it is important that staff are well supported in their roles.

Indexed as

Attitude of Health PersonnelNeoplasmsResearch PersonnelAdultAutopsyFemaleHumansInterviews as TopicMaleMiddle AgedQualitative Researchcancermetastasisoncologyprecision oncologyprofessional issuesqualitativerapid autopsy

Identifiers

PMID40347444
PMCPMC12065526

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.