Evidence map›Paper›PMID 40347291›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Comparison of paravertebral muscle thickness and fatty infiltration in patients with osteoporosis, osteopenia and normal bone mineral density: a single-blind retrospective controlled trial.

Aylin Ayyıldız, Selda Çiftci İnceoğlu, Hakan Ayyıldız, Banu Kuran

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Aylin AyyıldızÇam and Sakura City Hospital, Istanbul, Turkey. aylin.mrt93@gmail.com.
Selda Çiftci İnceoğluHamidiye Etfal Traning and Research Hospital, Istanbul, Turkey.
Hakan AyyıldızÇam and Sakura City Hospital, Istanbul, Turkey.
Banu KuranHamidiye Etfal Traning and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study was to investigate the effects of paravertebral muscles and fatty infiltrations of the lumbar region in individuals with varying degrees of bone mineral density, including those with osteoporotic, osteopenic, and healthy control groups.

methodsThis single-blind, retrospective, and controlled study included patients aged 50-90 years with lumbar magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry (DXA) measurements. The study sample was selected through a simple random sampling method. The patients were divided into three groups based on their T-values in DXA measurements. All patients were evaluated using MRI to measure the anteroposterior thickness of the multifidus, psoas, and erector spinae muscles. Additionally, the Goutallier classification was utilized to assess the degree of muscle fatty infiltration at the L3 vertebra level.

resultsA total of 301 patients were included in the study. The mean age of the patients included in the study was 65.97 ± 8.15 years. A total of 274 patients (91%) were female. A notable reduction in the multifidus muscle was observed in both the osteoporotic and osteopenic groups when compared to the control group. A significant loss was observed in the erector spinae and psoas muscles in the osteoporotic group when compared to the osteopenic and control groups. Furthermore, a notable decline in erector spinae muscle mass was observed in the osteopenic group relative to the control group. The level of muscle fatty infiltration was found to be significantly higher in the osteoporotic group when compared to the control group.

conclusionIn patients with osteoporosis, there is a notable reduction in lumbar paravertebral muscle mass and an increase in fatty infiltration when compared to the healthy control group. The loss of muscle mass is observable in the multifidus and erector spinae muscles during the osteopenic period, whereas it is observable in the psoas muscle during the osteoporotic period.

Indexed as

Adipose TissueBone DensityBone Diseases, MetabolicOsteoporosisParaspinal MusclesAbsorptiometry, PhotonAgedAged, 80 and overFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesSingle-Blind MethodAdipose tissueMagnetic resonance imagingMuscleOsteoporosisSarcopenia

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.