ArticleActa anaesthesiologica Scandinavica2025
Optimal Analgesic Volume for Popliteal Plexus Block After Total Knee Arthroplasty: A Blinded RCT Protocol.
Article in Acta anaesthesiologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06908837 (Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty - a Randomized, Controlled, Blinded Study), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty - a Randomized, Controlled, Blinded Study
Who cites it
1 citing paper in PubMed.
- Popliteal Plexus Block as a Potential Alternative to IPACK Block in Total-Knee Arthroplasty: Anatomical Rationale, Clinical Evidence, and Ergonomic Advantages.Journal of clinical medicine · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundAdjunct treatment with a popliteal plexus block (PPB) provides moderate enhancement to multimodal analgesic regimens following total knee arthroplasty while maintaining motor function. However, the optimal anesthetic volume of local anesthetic for PPB remains unknown.
aimTo compare the analgesic effects of PPB with 10 versus 20 mL of local anesthetics as an adjunct to a femoral triangle block after total knee arthroplasty.
methodsThis blinded, controlled, randomized clinical trial will include 120 patients, randomly assigned to receive PPB with either 10 or 20 mL of bupivacaine 5 mg/mL. All patients undergo primary total knee arthroplasty under spinal anesthesia and receive a multimodal analgesia regimen, including paracetamol, ibuprofen, opioids, dexamethasone, and a femoral triangle block. OUTCOMES: Primary outcome is 24-h postoperative opioid consumption. Secondary outcomes include the frequency of patients with opioid-free analgesia in the first 24 h after surgery, postoperative pain intensity at rest and during mobilization, postoperative muscle function of the leg, ability to mobilize with crutches 6 h after surgery, and Quality of Recovery-15 survey at 24 h after surgery.
conclusionThis trial hopes to optimize postoperative pain management after total knee arthroplasty by providing valuable insights into the optimal analgesic volume for PPB.
trial registrationDanish Data Protection Agency: 693807, clinicaltrials.gov: NCT06908837, CTIS: 2024-520204-26-00.
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