Evidence map›Paper›PMID 40346725›Full record

ArticleJournal of the American Chemical Society2025

3,6-Anhydrogalactal as a Single-Addition Monomer for Chain-End Functionalization of Metathesis Polymers.

Zefeng Zhou, Quan Pham, Gavin J Giardino, Abhishek Chatterjee, Jia Niu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zefeng ZhouDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Quan PhamDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Gavin J GiardinoDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Abhishek ChatterjeeDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-6231-5302
Jia NiuDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-5622-6362

Funding

A genetically encoded toolset to decipher the biology of post-translational modifications in the mammalian proteomeR35GM136437 · NIGMS · BOSTON COLLEGE · PI Abhishek Chatterjee · 2020 to 2026
$4.0M
CryoProbe-enabled Bruker AVANCE NEO 500 MHz NMR SpectrometerS10OD026910 · OD · BOSTON COLLEGE · PI JAYASUNDERA, THUSITHA · 2021 to 2021
$1000k
NIGMS NIH HHS R35 GM136437NIH HHS S10 OD026910
6 · The paper itself

Abstract

Controlling the structure and reactivity of the chain-end group is a central objective in modern polymer chemistry. Here we introduce 3,6-anhydrogalactal as a single-addition monomer that enables efficient and versatile chain-end functionalization of metathesis polymers. Readily synthesized from biomass-derived galactal, 3,6-anhydrogalactal exhibits excellent single-addition reactivity, allowing precise chain-end modifications even when introduced simultaneously with the propagating monomer. Theoretical calculations provide mechanistic insights into the unique reactivities governing its single-addition behavior. Its broad functional group compatibility facilitates diverse applications, including block copolymer synthesis, polymer-polymer coupling, and bioconjugation, demonstrating significant potential for advancing polymer materials and bioconjugation strategies.

Identifiers

PMID40346725
PMCPMC12425655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.