ArticleArchives of public health = Archives belges de sante publique2025
Young adults' knowledge, attitudes, and practices regarding premarital screening for genetic blood disorders and associated sociodemographic determinants in the Ahafo Region of Ghana: a cross-sectional study.
Article in Archives of public health = Archives belges de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Negotiating genetic risk in Indonesia: Development and psychometric evaluation of the knowledge and attitude toward consanguineous marriage instrument in a mixed-methods cross-sectional study.Journal of community genetics · 2026Article
- Genetic blood disorder status awareness and factors influencing willingness or reluctance to undergo premarital screening among young adults in Ahafo Region, Ghana: a cross-sectional survey.Journal of health, population, and nutrition · 2026Article
- Knowledge, attitudes, and perceptions towards premarital screening among undergraduate university students in Chattogram district, Bangladesh: a cross-sectional study.BMC public health · 2026Article
- Hemoglobin Phenotype Distribution Among Future Healthcare Providers: A Descriptive Cross-Sectional Study at a Ghanaian Health Sciences University.TheScientificWorldJournal · 2026Article
- Article
- Assessment of the knowledge, attitude, and future practices toward the concept of premarital screening among unmarried Lebanese adults: A cross-sectional study.PLOS global public health · 2026Article
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Abstract
backgroundHereditary diseases, particularly genetic blood disorders such as Sickle Cell Disease (SCD), Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, and Thalassemia, pose significant public health challenges. Premarital carrier screening (PMCS) is a critical preventive measure, yet its uptake remains low in many regions, including the Ahafo Region of Ghana. This study assessed young adults' knowledge, attitudes, and practices (KAP) regarding PMCS for SCD, G6PD deficency, and Thalassemia and determined factors associated with these KAP outcomes in the Ahafo Region.
methodsA cross-sectional study was conducted from January to March 2024, involving 460 young adults aged 18-35 years attending various health facilities in the Ahafo Region. Data were collected using a validated structured questionnaire, translated into the local dialect for clarity. The questionnaire covered socio-demographic information, knowledge of PMCS, attitudes towards PMCS, and PMCS practices. Data were analysed using Stata version 14, with descriptive statistics, Chi-square tests for associations, and logistic regression to identify significant predictors of KAP.
resultsThe study population was predominantly female (85.7%), with a mean age of 24.7 years. Only 15.4% (n = 71) of respondents demonstrated good knowledge of PMCS. Key factors influencing knowledge included female gender, age 26-35 years, tertiary education, and receiving information from healthcare services. Positive attitudes towards PMCS were observed in 66.7% of respondents, significantly associated with tertiary education, self-employment, unemployment, and cohabiting marital status. However, only 14.1% exhibited positive PMCS practices, with significant predictors being tertiary education and being married. These findings indicate a substantial gap between awareness and actual practice of PMCS.
conclusionThis study underscores the urgent need for targeted educational interventions and policy measures to enhance PMCS uptake among young adults in the Ahafo Region. Improving healthcare communication, integrating PMCS education into tertiary curricula, addressing sociocultural barriers, and enacting supportive policies are essential steps. Engaging various stakeholders, including healthcare providers, educational institutions, community leaders, policymakers, and NGOs, is crucial for effectively translating positive attitudes into proactive practices and reducing the prevalence of genetic blood disorders in the Ahafo Region and Ghana as a whole.
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