Evidence map›Paper›PMID 40346595›Full record

SynthesisSystematic reviews2025

Interventions to improve referrals from primary care to outpatient specialist services for chronic conditions: a systematic review and framework synthesis update.

Layla Bolton Saghdaoui, Smaragda Lampridou, Sara Tavares, Rachael Lear, Alun Huw Davies, Mary Wells, Sarah Onida

Abstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  5. Defining a theoretical framework for a quality referral at the primary-secondary care interface: a systematic scoping review with qualitative content analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Layla Bolton SaghdaouiSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, Fulham Palace Rd, 4th Floor (North), Vascular Outpatients, Room 4N22C, London, W6 8RF, UK. layla.boltonsaghdaoui@nhs.net.ORCID 0000-0003-1229-773X
Smaragda LampridouSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, Fulham Palace Rd, 4th Floor (North), Vascular Outpatients, Room 4N22C, London, W6 8RF, UK.
Sara TavaresHanwell Health Centre, School of Public Health, Imperial College London, London, W7 1DR, UK.
Rachael LearDigitial Collaboration Space, Imperial College London, 1A Sheldon Square, W2 6PY, Queen Elizabeth the Queen Mother Wing (QEQM), St Mary's Campus, London, UK.
Alun Huw DaviesSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, Fulham Palace Rd, 4th Floor (North), Vascular Outpatients, Room 4N22C, London, W6 8RF, UK.
Mary WellsFaculty of Medicine, Education Centre, Charing Cross Hospital, Imperial College London, Fulham Palace Rd, London, W6 8RF, UK.
Sarah OnidaSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, Fulham Palace Rd, 4th Floor (North), Vascular Outpatients, Room 4N22C, London, W6 8RF, UK.

Funding

National Institute for Health and Care Research NIHR302917
6 · The paper itself

Abstract

backgroundPrior systematic reviews highlight that accessing specialist healthcare to treat chronic conditions can be obstructed by variations in referral rates, inappropriate referrals, and poor communication. Structured referral proformas, peer feedback, and educational interventions involving specialists have been identified as successful strategies for improving referral rates and appropriateness. However, the success of such interventions is often dependent on specific clinical contexts, and little is known about the practicalities of implementation. Additionally, with advancements in healthcare delivery, such as e-referral systems, there is a need to explore new interventions and how they address barriers to referral.

methodsThis systematic review evaluated the updated evidence exploring interventions aiming to improve rates and/or appropriateness of referral from primary care to specialist services in patients with chronic conditions.Five academic databases were searched (CINAHL, MEDLINE, Embase, British Nursing Index, and Public Health Database), and studies published in English between 2013 and 2023 were included. The Joanna Briggs Institute's appraisal tool was used to assess the quality of studies, and a narrative synthesis was conducted using the TiDiER framework (template for intervention description and replication).

resultsEighteen full-text publications and five abstracts were included. A behavioral theory or framework for intervention development was used in seven studies. All interventions were based on primary care, and thirteen studies evaluated a multi-component intervention. Process and system changes were most commonly used to improve referral, including electronic health systems, referral algorithms, collaborative working, and patient direct access. Interventions targeted at patients were the least common. Staff education was often used in addition to process and system changes. When used alone, referral algorithms and staff education were less effective at improving referral rates or appropriateness. Implementation barriers included time constraints, logistical issues, and patients/staff preconceived perceptions of referral necessity.

conclusionUnsurprisingly, the success of interventions aimed at improving referral practices is based on contextual circumstances, and as with previous reviews, there is no one-size-fits-all approach.Given the challenges highlighted in this review, multi-component interventions addressing referral barriers in both primary and secondary care appear to be a successful way to improve referral practices. REVIEW REGISTRATION: PROSPERO CRD42023480493.

Indexed as

Ambulatory CarePrimary Health CareReferral and ConsultationSpecializationChronic DiseaseHumansChronic conditionsPrimary careReferralSpecialist services

Identifiers

PMID40346595
PMCPMC12063302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.