Evidence map›Paper›PMID 40346556›Full record

SynthesisBMC plant biology2025

Unravelling consensus genomic regions conferring stem-related traits in wheat via meta-QTL analysis.

Yongping Miao, Lei Wu, Fanli Jing, Jiaru Yang, Hong Ye, Mang Shen, Ke Zhou, Yangyifan He, Xin Liu, Ming Hao and 7 more

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yongping Miao *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Lei Wu *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Fanli JingTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Jiaru YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Hong YeState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Mang ShenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Ke ZhouState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Yangyifan HeState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Xin LiuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Ming HaoTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Bo JiangTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Lin HuangTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Shunzong NingTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Xuejiao ChenTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Xue ChenTriticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China.
Dengcai LiuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China. dcliu7@sicau.edu.cn.
Lianquan ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, Wenjiang, China. zhanglianquan1977@126.com.ORCID http://orcid.org/0000-0001-9005-8705

Funding

Key Research and Development Program of Sichuan Province, China 2021YFYZ0002Sichuan Science and Technology Program 2022ZDZX0016
6 · The paper itself

Abstract

backgroundWheat stem is an important vegetative organ, that is responsible for supporting leaves and spikes, and transporting water, minerals and organic nutrients to spikes through vascular bundles, thereby promoting plant growth and development. Therefore, wheat stems contribute to plant structure and total yield.

resultsWe constructed a high-density consensus map and performed a meta-analysis using 306 stem-related QTLs. The results revealed 45 meta-QTLs (MQTLs) with a mean confidence interval (CI) 4.50 times lower than that of the original QTL. A total of 25/31 MQTLs (PI < 100 Mb) overlapped with SNP-trait associations reported in genome-wide association studies (GWASs). By associating MQTL interval genes with multiomics datasets and performing coexpression analysis of common genes, we generated a more reliable and concise list of putative candidate genes involved in stem regulation. Furthermore, we identified an ethylene-responsive transcription factor in the form of TraesCS5B02G236900 haplotype, whose variations may be related to stem-related traits.

conclusionIn this study, comprehensive analysis was used to determine the most stable loci on a high-density consensus map associated with reliable genetic markers, and MQTLs, candidate genes and excellent haplotypes were identified, which laid a foundation for further research on the genetic basis of wheat stem development and promoted the development of wheat molecular breeding.

Indexed as

Genome, PlantPlant StemsQuantitative Trait LociTriticumChromosome MappingConsensus SequenceGenes, PlantGenome-Wide Association StudyHaplotypesPhenotypePolymorphism, Single NucleotideCandidate genesHaplotypesMeta-QTLStemWheat

Identifiers

PMID40346556
PMCPMC12063419

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.