Evidence map›Paper›PMID 40346438›Full record

SynthesisLasers in medical science2025

Using violet light during in-office tooth bleaching to enhance the efficacy of carbamide peroxide without increasing bleaching sensitivity: a systematic review and meta-analysis.

Mariana Silva de Bessa, Kaiza de Sousa Santos, Patrick Wesley Marques de Boa, Francisca Jennifer Duarte de Oliveira, Bárbara Faria de Sá Barbosa, Boniek Castillo Dutra Borges

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mariana Silva de BessaUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil.
Kaiza de Sousa SantosUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil.
Patrick Wesley Marques de BoaUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil.
Francisca Jennifer Duarte de OliveiraUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil.
Bárbara Faria de Sá BarbosaUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil.
Boniek Castillo Dutra BorgesUniversidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil. boniek.castillo@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis evaluated whether irradiating carbamide peroxide (CP) with violet light can enhance the effect of in-office tooth bleaching without increasing sensitivity. Searches were conducted in PubMed, Embase, Scopus, Web of Science, and Google Scholar databases. Randomized clinical trials (RCTs) that performed in-office tooth bleaching with CP irradiated with violet light or not were included in all languages ​​and years of publication. The systematic steps followed the PRISMA protocol. The risk of bias was assessed by the RoB 2 tool. The GRADE was used to analyze the certainty of evidence. Meta-analysis was conducted with RevMan 5.4 software to evaluate tooth color change (CC) and bleaching sensitivity (BS). The CC was assessed by mean difference (MD) and the BS by risk difference (RD). Three RCTs were included in this systematic review. A statistically significant difference for CC favoring the application of violet light associated with the CP (MD, 3.35; 95% CI, 0.80, 5.89) was obtained, while no difference was found for BS (RD, 0.09; 95% CI, -0.03, 0.21). Violet light irradiation improved carbamide peroxide's in-office tooth bleaching effect without increasing sensitivity. However, the results should be interpreted with caution due to the moderate certainty of the evidence.

Indexed as

Carbamide PeroxideTooth BleachingTooth Bleaching AgentsDentin SensitivityHumansLightRandomized Controlled Trials as TopicCarbamide PeroxideTooth Bleaching AgentsCarbamide peroxideMeta-analysisSystematic reviewTooth bleachingTooth sensitivity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.