Evidence map›Paper›PMID 40346304›Full record

ArticleClinical neuroradiology2025

Visualization of Culprit Perforating Artery in Subcortical Infarction Using 3D MRI and Angiography Fusion Image.

Junpei Koge, Shiori Ogura, Kanta Tanaka, Shuhei Egashira, Takeshi Yoshimoto, Masayuki Shiozawa, Yasutoshi Ohta, Tetsuya Fukuda, Masafumi Ihara, Kazunori Toyoda and 1 more

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Article in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Junpei KogeDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan. j.kouge@gmail.com.ORCID http://orcid.org/0000-0002-9632-2164
Shiori OguraDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan.
Kanta TanakaDivision of Stroke Care Unit, National Cerebral and Cardiovascular Center, Suita, Japan.
Shuhei EgashiraDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan.
Takeshi YoshimotoDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Masayuki ShiozawaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan.
Yasutoshi OhtaDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Tetsuya FukudaDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Masafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kazunori ToyodaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan.
Masatoshi KogaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, 564-8565, Suita, Osaka, Japan.

Funding

Japan Society for the Promotion of Science London 20K16716
6 · The paper itself

Abstract

purposeVisualizing the culprit perforating artery in subcortical infarction using in vivo imaging is challenging. We aimed to identify the culprit perforating arteries in subcortical infarctions and assess their morphology using an image fusion technique.

methodsWe retrospectively reviewed consecutive patients who had an ischemic stroke in the anterior circulation perforating area (caudate nucleus, lentiform nucleus, internal capsule, corona radiata, or centrum semiovale) and underwent three-dimensional rotational-angiography (3D-RA) and 3D fluid-attenuated inversion recovery MRI. Images were registered using an original fusion software. The spatial relationship between the infarction and culprit perforating artery and its morphological characteristics were analyzed in the fusion images. Stenosis was defined as > 50% luminal narrowing or a focal intraluminal defect in the perforating artery.

resultsOf 118 patients, the culprit perforating artery was identified in 52 patients (44%); They tended to have younger age and had a higher baseline NIHSS score and higher prevalence of infarcts in the lentiform nucleus than did those without identified culprit perforating artery. Among the 44 patients with assessable morphology of the culprit perforating artery, 27 (61%) exhibited stenosis in the proximal segment. Atrial fibrillation was more frequent in patients without stenosis in the proximal segment of the culprit perforating artery than in those with stenosis (29% vs. 4%, P = 0.03).

conclusionThe 3D-RA and MRI fusion technique enables identification of the culprit perforating arteries in subcortical infarctions, especially in the lentiform nucleus. Morphological features of the culprit perforating artery may be associated with the etiological mechanism of stroke.

Indexed as

Cerebral AngiographyCerebral InfarctionImaging, Three-DimensionalMagnetic Resonance AngiographyMagnetic Resonance ImagingAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesAcute ischemic strokeCerebral angiographyLenticulostriateMagnetic resonance imagingSubcorical infarction

Identifiers

PMID40346304

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