Evidence map›Paper›PMID 40346299›Full record

Observational studyInternational urology and nephrology2025

Prospective analysis of the morcellation efficiency of a novel device (MultiCut®) for prostate laser enucleation.

Borja García-Gómez, Javier Gil-Moradillo, Ignacio Sola-Galarza, Alfonso Gimeno-Collado, Lucía García-González, Antonio Fidel Campoy-Pérez, Amparo Andrés-Ramos, Alfredo Rodríguez-Antolín

Abstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Borja García-GómezDepartment of Urology, Salud Integral del Varón, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Córdoba Avenue, 28041, Madrid, Spain. borjagarciagomez@gmail.com.
Javier Gil-MoradilloDepartment of Urology, Salud Integral del Varón, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Córdoba Avenue, 28041, Madrid, Spain.
Ignacio Sola-GalarzaLyx Instituto de Urología, Universidad Francisco de Vitoria, Madrid, Spain.
Alfonso Gimeno-ColladoLyx Instituto de Urología, Universidad Francisco de Vitoria, Madrid, Spain.
Lucía García-GonzálezDepartment of Urology, Salud Integral del Varón, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Córdoba Avenue, 28041, Madrid, Spain.
Antonio Fidel Campoy-PérezDepartment of Urology, Salud Integral del Varón, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Córdoba Avenue, 28041, Madrid, Spain.
Amparo Andrés-RamosLyx Instituto de Urología, Universidad Francisco de Vitoria, Madrid, Spain.
Alfredo Rodríguez-AntolínDepartment of Urology, Salud Integral del Varón, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Córdoba Avenue, 28041, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the efficiency and safety of the MultiCut Solo® morcellator in patients undergoing holmium laser enucleation of the prostate (HoLEP), and to analyze the influence of device settings, surgeon experience, and blade reuse on morcellation outcomes.

methodsThis prospective, multicenter, observational study included 232 patients undergoing HoLEP from January to September 2023 across two high-volume centers in Madrid, Spain. Three morcellation settings were evaluated: reduction, fast, and slow modes. Data on morcellation efficiency (g/min), surgeon experience (expert vs. trainee), and blade use frequency (0-10) were collected. Efficiency and complication rates were compared across groups. Statistical analysis was performed using Student's t-tests and Pearson's correlation.

resultsA total of 326 morcellation instances were analyzed. Mean global morcellation efficiency was 14.5 g/min (SD ± 7.6), with reduction, fast, and slow modes yielding 16.7, 12.5, and 8.5 g/min, respectively. Surgeons' experience showed a non-significant trend toward higher efficiency (15.2 vs. 13.1 g/min, p = 0.051). Blade reuse up to 10 times did not significantly affect performance. Bladder perforation occurred in 1.29% of cases, and hematuria requiring temporary morcellation suspension in 3.88%. Obstruction occurred in 31.47% of cases, but disassembly was only required in 8.19%.

conclusionsThe MultiCut Solo® morcellator demonstrated high efficiency and a favorable safety profile. Efficiency was consistent across surgeon experience levels and was not significantly impacted by blade reuse within the manufacturer's recommended lifespan. These findings suggest that the device is effective and user-friendly, even in the early learning curve, and represents a valuable tool for tissue morcellation in HoLEP procedures.

Indexed as

Lasers, Solid-StateLaser TherapyMorcellationProstatectomyProstatic HyperplasiaAgedEquipment DesignHumansMaleMiddle AgedProspective StudiesEndoscopic enucleationHoLEPLaser enucleationMorcellation efficiencyProstate

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.