ReviewNature reviews. Chemistry2025
Terahertz calorimetry spotlights the role of water in biological processes.
Review in Nature reviews. Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Spiers Memorial Lecture: Vibrations at interfaces.Faraday discussions · 2026Article
- Breaking the Air-Water Paradigm: Ion Behavior at Hydrophobic Solid-Water Interfaces.Journal of the American Chemical Society · 2026Article
- Single-engineered-residue solvation perturbations regulate global protein architecture and function.Nature communications · 2026Article
- Molecular Scale Hydrophobicity and Adsorption Thermodynamics on Hydrophobic-Charged Surfaces.ACS nano · 2026Article
- Dynamics of Solvating Water As a Probe of Polymers and Supramolecular Structures.Chemical reviews · 2026Review
- Water-mediated hydrogen bonds and local side-chain interactions in the cooperative collapse and expansion of PNIPAM oligomers.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Exploring Water Beyond the Solvent: Insights into Density Fluctuations and EGFP Unfolding via Luminescence Thermometry.The journal of physical chemistry. B · 2025Article
- Hydraulic Activation of the AsLOV2 Photoreceptor.bioRxiv : the preprint server for biology · 2025Article
- Advances in Terahertz Biophysics and Chemistry.Research (Washington, D.C.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terahertz (THz) calorimetry is a framework that allows for the deduction and quantification of changes in solvation entropy and enthalpy associated with biological processes in real-time. Fundamental biological processes are inherently non-equilibrium, and a small imbalance in free energy can trigger protein condensation or folding. Although biophysical techniques typically focus mainly on structural characterization, water is often ignored. Being a generic solvent, the intermolecular protein-water interactions act as a strong competitor for intramolecular protein-protein interactions, leading to a delicate balance between functional structure formation and complete solvation. Characteristics for biological processes are large, but competing enthalpic and entropic solvation contributions to the total Gibbs free energy lead to subtle energy differences of only a few kJ mol
Indexed as
Identifiers
40346278What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.