Evidence map›Paper›PMID 40346048›Full record

ArticleNature communications2025

Insight predicts subsequent memory via cortical representational change and hippocampal activity.

Maxi Becker, Tobias Sommer, Roberto Cabeza

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maxi BeckerHumboldt University Berlin, Department of Psychology, Berlin, Germany. maxi_becker@gmx.net.ORCID http://orcid.org/0000-0002-9430-4077
Tobias SommerUniversity Medical Center Hamburg-Eppendorf, Institute of Systems Neuroscience, Hamburg, Germany.
Roberto CabezaHumboldt University Berlin, Department of Psychology, Berlin, Germany.

Funding

Effects of Healthy Aging and Mild Cognitive Impairment on Memory RepresentationsRF1AG066901 · NIA · DUKE UNIVERSITY · PI CABEZA, ROBERTO · 2021 to 2021
$2.3M
Einstein Stiftung Berlin (Einstein Foundation Berlin) EPP-2017-423NIA NIH HHS RF1 AG066901
6 · The paper itself

Abstract

The neural mechanisms driving creative problem-solving, including representational change and its relation to memory, still remain largely unknown. We focus on the creative process of insight, wherein rapid knowledge reorganization and integration-termed representational change-yield solutions that evoke suddenness, certainty, positive emotion, and enduring memory. We posit that this process is associated with stronger shifts in activation patterns within brain regions housing solution-relevant information, including the visual cortex for visual problems, alongside regions linked to feelings of emotion, suddenness and subsequent memory. To test this, we collect participants' brain activity while they solve visual insight problems in the MRI. Our findings substantiate these hypotheses, revealing stronger representational changes in visual cortex, coupled with activations in the amygdala and hippocampus-forming an interconnected network. Importantly, representational change and hippocampal effects are positively associated with subsequent memory. This study provides evidence of an integrated insight mechanism influencing memory.

Indexed as

HippocampusMemoryVisual CortexAdultAmygdalaBrain MappingEmotionsFemaleHumansMagnetic Resonance ImagingMaleProblem SolvingYoung Adult

Identifiers

PMID40346048
PMCPMC12064812

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.