Evidence map›Paper›PMID 40346022›Full record

ArticleACS nano2025

Scavenging Reactive Oxygen Species by Cerium Oxide Nanoparticles Prevents Death in a Peripheral T Cell Lymphoma Preclinical Mouse Model.

Adrien Krug, Lena M Ernst, Rana Mhaidly, Joana Ramis, Muriel F Gusta, Neus G Bastus, Adriana Martinez-Turtos, Marie Tosolini, Léa Di Mascio, Gamze Tari and 6 more

Abstract read
In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Adrien KrugUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Lena M ErnstVall d'Hebron Research Institute (VHIR), Passeig Vall d'Hebron 119-129, Barcelona 08035, Spain.
Rana MhaidlyUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Joana RamisVall d'Hebron Research Institute (VHIR), Passeig Vall d'Hebron 119-129, Barcelona 08035, Spain.
Muriel F GustaVall d'Hebron Research Institute (VHIR), Passeig Vall d'Hebron 119-129, Barcelona 08035, Spain.
Neus G BastusVall d'Hebron Research Institute (VHIR), Passeig Vall d'Hebron 119-129, Barcelona 08035, Spain.ORCID 0000-0002-3144-7986
Adriana Martinez-TurtosUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Marie TosoliniCRCT, Université de Toulouse, Inserm, CNRS, Université Toulouse III-Paul Sabatier, Centre de Recherches en Cancérologie de Toulouse, Toulouse 31100, France.
Léa Di MascioUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Gamze TariINSERMU955; Unité hémopathies lymphoïdes, Hôpitaux Universitaires Henri Mondor, Assistance publique des Hôpitaux de Paris, Université Paris-Est Créteil; Institut Mondor de Recherche Biomédicale, Créteil F-94010, France.
Laurent BoyerUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Philippe Gaularddépartement de pathologie, AP-HP, Groupe hospitalo-universitaire Chenevier Mondor, Créteil F-94010, France.
François LemonnierINSERMU955; Unité hémopathies lymphoïdes, Hôpitaux Universitaires Henri Mondor, Assistance publique des Hôpitaux de Paris, Université Paris-Est Créteil; Institut Mondor de Recherche Biomédicale, Créteil F-94010, France.
Jean-Ehrland RicciUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.
Els VerhoeyenUniversité Côte d'Azur, INSERM, C3M, Nice 06204, France.ORCID 0000-0001-9224-5491
Victor PuntesVall d'Hebron Research Institute (VHIR), Passeig Vall d'Hebron 119-129, Barcelona 08035, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cell survival and proliferation are correlated with increased metabolic activity and consequent oxidative stress, driving metabolic shifts that interfere with the immune response to malignant cells. This is the case of high-energy-demanding angioimmunoblastic T cell lymphoma (AITL), a highly aggressive cancer with poor survival rates, where malignant CD4+ PD-1

Indexed as

CeriumFree Radical ScavengersLymphoma, T-CellNanoparticlesReactive Oxygen SpeciesAnimalsDisease Models, AnimalMiceMice, Inbred C57BLceric oxideCeriumFree Radical ScavengersReactive Oxygen SpeciesAITL preclinical modelantioxidantcancercerium oxide nanoparticlesmitochondriaROST cell lymphoma

Identifiers

PMID40346022
PMCPMC12512179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.