Evidence map›Paper›PMID 40346014›Full record

ArticleJournal of anatomy2026

Intramuscular tendon length in agonist-antagonist myoneural interface components in transtibial amputation: An anatomic study.

Viktoria Witowski, Lisa Lorbeer, Laura Schmid, Benedict Wilhelmi, Victor A Hoursch, Matthew J Carty, Hugh M Herr, Roland Blumer, Massimo Sartori, Utku Ş Yavuz and 4 more

Abstract read
In one paragraph

Article in Journal of anatomy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clarifying Proprioceptive Training: A Narrative Review.Journal of functional morphology and kinesiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Viktoria WitowskiHannover Medical School, Department of Trauma Surgery, Hannover, Germany.ORCID https://orcid.org/0009-0005-8980-9758
Lisa LorbeerHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Laura SchmidInstitute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Stuttgart, Germany.
Benedict WilhelmiHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Victor A HourschHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Matthew J CartyDivision of Plastic Surgery, Brigham & Women's Hospital, Boston, Massachusetts, USA.
Hugh M HerrMassachusetts Institute of Technology, Center for Extreme Bionics, Cambridge, Massachusetts, USA.
Roland BlumerCenter of Anatomy and Cell Biology, Division of Anatomy, Medical Image Cluster, Medical University Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0001-5048-4865
Massimo SartoriDepartment of Biomechanical Engineering, University of Twente, Enschede, Netherlands.
Utku Ş YavuzBiomedical Signals and Systems, University of Twente, Enschede, Netherlands.
Corey L SullivanDivision of Plastic Surgery, Brigham & Women's Hospital, Boston, Massachusetts, USA.
Stephan SehmischHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Andreas SchmiedlHannover Medical School, Institute of Functional and Applied Anatomy, Hannover, Germany.ORCID https://orcid.org/0000-0002-0698-0121
Jennifer ErnstHannover Medical School, Department of Trauma Surgery, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the role of tendons in muscle function and proprioception is crucial for enhancing amputation surgery. Muscle spindles and Golgi tendon organs provide essential feedback for muscle control. Preservation of tendon function in amputation surgery and the development of the agonist-antagonist myoneural interface (AMI) have shown promising results restoring muscle-tendon proprioception and in improving prosthetic control. However, challenges remain in constructing AMI due to anatomical limitations in residual limbs. A total of 25 lower legs from fresh-frozen human Caucasian donors were dissected, and the muscles relevant to the AMI technique, such as the gastrocnemius complex, the tibialis posterior, the tibialis anterior, and the peroneus longus, were analyzed. Demographic and anthropometric measurements, muscle preparation and weight, markings, imaging, and statistical analysis methods were described in detail. In all muscles examined, the intramuscular course of the tendon extended over more than 75% of the distal muscle belly. The muscle belly length of the peroneus longus muscle and the medial head of the gastrocnemius muscle showed a significant positive correlation with the weight and height of the donors. There were no significant correlations between the ratio of the intramuscular course of the tendon to muscle belly length and the weight or height of the donor. The AMI technique can enhance proprioceptive feedback for transtibial amputees wearing prostheses. The study indicates that gender does not impact muscle characteristics, but weight and height show correlations. These results offer valuable insights into muscle anatomy for informing future research on the functional effects of AMI and prosthetic limb design.

Indexed as

Amputation, SurgicalLegMuscle, SkeletalTendonsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProprioceptionTibiaagonist–antagonist muscle strainagonist–antagonist myoneural interfaceanatomyfunctional limb restorationlower extremitymechanoneural interfacesmuscle architecturemuscle–tendon lengthproprioception

Identifiers

PMID40346014
PMCPMC13140445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.