Evidence map›Paper›PMID 40345691›Full record

ArticleBMJ open2025

Prevalence of microspirometry-detected chronic obstructive pulmonary disease in two European cohorts of patients hospitalised for acute myocardial infarction: a cross-sectional study.

William A E Parker, Josefin Sundh, Jonas Oldgren, Pontus Andell, Christian Reitan, Tomas Jernberg, Robin Hofmann, Moman A Mohammad, David Erlinge, Axel Akerblom and 13 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

William A E Parker *Cardiovascular Research Unit, The University of Sheffield, Sheffield, UK w.parker@sheffield.ac.uk.ORCID http://orcid.org/0000-0002-7822-8852
Josefin Sundh *Department of Respiratory Medicine, Orebro Universitet, Orebro, Sweden.
Jonas OldgrenMedical Sciences, Uppsala University, Uppsala, Sweden.
Pontus AndellDepartment of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Christian ReitanDepartment of Clinical Science, Karolinska Institutet, Stockholm, Sweden.
Tomas JernbergDepartment of Clinical Science, Karolinska Institutet, Stockholm, Sweden.
Robin HofmannDepartment of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Stockholm, Sweden.
Moman A MohammadDepartment of Cardiology, Clinical Sciences, Lunds Universitet, Lund, Sweden.ORCID http://orcid.org/0000-0003-4242-9801
David ErlingeDepartment of Cardiology, Clinical Sciences, Lunds Universitet, Lund, Sweden.
Axel AkerblomMedical Sciences, Uppsala University, Uppsala, Sweden.
Sofia Sederstam LawessonDepartment of Cardiology Department of Health, Medicine and Caring Sciences, Linköping University, Linkoping, Sweden.
Kyriakos V KonstantinidisProjects, Early Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Johan LindbäckUppsala Clinical Research Center, Uppsala, Sweden.
Christer JansonMedical Sciences, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5093-6980
Anna BjörkenheimDepartment of Cardiology, Örebro University Hospital, Orebro universitet, Orebro, Sweden.ORCID http://orcid.org/0000-0002-4288-3310
Nadir ElaminCardiovascular Research Unit, Division of Clinical Medicine, University of Sheffield, Sheffield, UK.
Hannah McMellonCardiovascular Research Unit, Division of Clinical Medicine, University of Sheffield, Sheffield, UK.
Bethany MoyleCardiovascular Research Unit, Division of Clinical Medicine, University of Sheffield, Sheffield, UK.
Mehul PatelClinical Development, Late Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Jad El-KhouryGlobal Medical Affairs, Respiratory, BioPharmaceutical Medical, AstraZeneca plc, London, UK.
Raulin SurujballyClinical Operations - Late Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Robert F Storey *Cardiovascular Research Unit, The University of Sheffield, Sheffield, UK.
Stefan K James *Medical Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo establish the prevalence of clinically significant chronic obstructive pulmonary disease (COPD) and relevant characteristics in individuals with a significant smoking history who are hospitalised for acute myocardial infarction (MI).

designCross-sectional study.

settingHospital inpatients at 8 European centres (7 in Sweden, 1 in the UK).

participants518 men or women (302 in Sweden, 216 in the UK) hospitalised for acute MI, aged 40 years or older, with a smoking history of at least 10 pack-years. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was prevalence of detected significant COPD (Global Initiative for Chronic Obstructive Lung Disease stages 2-4), defined as a ratio of forced expiratory volume in 1 and 6 s (FEV

resultsThe prevalence of significant COPD was 91/518 (18% (95% CI 14 to 21)) with no difference between the countries. Of those with detected significant COPD, 69 (76%) had no previous COPD diagnosis. A CAT score >10 was found in 65%, and a blood eosinophil count of ≥100/mm

conclusionsIn a cohort of patients hospitalised for acute MI in Sweden and the UK, one in five patients with a history of smoking was found to have significant COPD based on microspirometry. Symptom burden was high and treatment rates with ICS low. Among those diagnosed with COPD, three out of four had not been previously diagnosed with COPD.

Indexed as

Myocardial InfarctionPulmonary Disease, Chronic ObstructiveSmokingAdrenal Cortex HormonesAdultAgedCross-Sectional StudiesFemaleForced Expiratory VolumeHospitalizationHumansMaleMiddle AgedPrevalenceSwedenUnited KingdomAdrenal Cortex HormonesEpidemiologyMyocardial infarctionPulmonary Disease, Chronic ObstructiveRespiratory Function Test

Identifiers

PMID40345691
PMCPMC12067773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.