Trial reportJournal of sleep research2026
Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Outpatients With Sleep Problems and Depression, Attention Deficit Disorder, or Bipolar Disorder: A Randomised Controlled Trial.
Trial report in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transdiagnostic effects of combined sleep-circadian interventions on depressive symptoms and sleep outcomes in adults with mental disorders: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2026Pooled it
- Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Outpatients With Sleep Problems and Depression, Attention Deficit Disorder, or Bipolar Disorder: A Randomised Controlled Trial.Journal of sleep research · 2026Trial
- Electronic self-monitored morning depression scores are related to sleep timing and sleep length in depressed patients.Npj biological timing and sleep · 2026Article
- Behavioral Sleep Interventions for Neurodivergent Youth: A Narrative Review.Current sleep medicine reports · 2026Review
- Advanced biomaterials and digital twins for precision psychiatry: neuroimmune modulation and AI-guided therapeutics.Frontiers in bioengineering and biotechnology · 2026Article
- The association between heart rate variability and inflammatory markers in first-episode depressed patients with different sleep quality.BMC psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study aimed to investigate the efficacy of a Danish adaption of a transdiagnostic sleep and circadian intervention, combining cognitive behavioural therapy for insomnia with chronotherapy. A randomised controlled trial enrolling 88 outpatients with depression, attention deficit disorder, or bipolar disorder suffering from insomnia or circadian rhythm disorders was conducted. Patients with insomnia and/or circadian rhythm disorders were randomised to either an intervention group receiving six individual sessions of a transdiagnostic sleep and circadian intervention or a control group receiving sleep hygiene education at a single session. Primary outcome was sleep quality and insomnia severity. Secondary outcomes were well-being, personal recovery, work ability, perceived overall health, sleep efficiency, sleep onset latency, wake after sleep onset, nocturnal awakenings, and sleep medication consumption. Data were collected via validated questionnaires, actigraphy, and sleep diaries, with assessments at baseline, week 2, and 6; actigraphy and sleep diaries were recorded continuously over the 6-week period. The intervention group statistically significantly improved sleep quality (p < 0.001), reduced insomnia severity (p < 0.001), and increased well-being (p = 0.002), personal recovery (p = 0.037), work ability (p < 0.001), and perceived overall health (p = 0.004) from baseline to week 6 compared to the control group. Actigraphy and sleep diary analyses revealed no statistically significant differences between the groups. In conclusion, the transdiagnostic sleep and circadian intervention was effective for both patients with insomnia and circadian rhythm disorders comorbid with depression, attention deficit disorder, or bipolar disorder. It resulted in improved sleep quality, a reduction in insomnia, and enhanced well-being, personal recovery, work ability, and overall health perception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.