Evidence map›Paper›PMID 40344522›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Reconstructing Three-Dimensional Optical Anisotropy with Tomographic Müller-Polarimetric Microscopy.

Yang Chen, Arthur Baroni, Torne Tänzer, Leonard Nielsen, Marianne Liebi

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang ChenCenter for Photon Science, Paul Scherrer Institut, Villigen PSI, 5232, Switzerland.ORCID https://orcid.org/0000-0003-4643-646X
Arthur BaroniCenter for Photon Science, Paul Scherrer Institut, Villigen PSI, 5232, Switzerland.ORCID https://orcid.org/0000-0003-4294-7158
Torne TänzerCenter for Photon Science, Paul Scherrer Institut, Villigen PSI, 5232, Switzerland.ORCID https://orcid.org/0009-0009-5472-5836
Leonard NielsenDepartment of Physics, Chalmers University of Technology, Gothenburg, 41296, Sweden.ORCID https://orcid.org/0000-0002-5929-1127
Marianne LiebiCenter for Photon Science, Paul Scherrer Institut, Villigen PSI, 5232, Switzerland.

Funding

H2020 European Research Council ERC-2020-StG 949301
6 · The paper itself

Abstract

Most visible light imaging methods using polarization to obtain ultrastructure information are limited to 2D analysis or require demanding phase measurements to be extended to 3D. A novel 3D polarized light imaging technique based on Müller-matrix formulations is introduced which numerically reconstructs 3D optical birefringence, that is anisotropic refractive indices and optical axis orientation, in each volumetric unit of sample. The new method is demonstrated, tomographic Müller-polarimetric microscopy, in simulation and using experimental data of 3D macroscopic sample of human trabecular bone sample, where the local main orientation of nanoscale collagen fibers is extracted with a resolution of ≈ 20 µm. Tomographic Müller-polarimetric microscopy offers a low-cost and experimentally simple imaging approach to access the ultrastructure which is not directly resolvable, in a wide range of biological and composite materials.

Indexed as

3D ultrastructurebio‐imaginghuman trabecular bonereconstructiontomographic polarized light microscopy

Identifiers

PMID40344522
PMCPMC12279228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.