Observational studyDevelopmental medicine and child neurology2025
Respiratory admissions and impact of COVID-19 lockdowns for children with severe cerebral palsy.
Observational study in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Optimising respiratory health in children with neurodevelopmental impairment.Breathe (Sheffield, England) · 2026Review
- One Sample, Many Insights: The Epidemiological and Public Health Value of Multiplex PCR Respiratory Panels Following the End of the COVID-19 Pandemic.Microorganisms · 2026Article
- The potential hematological features of children with spastic cerebral palsy in China: a retrospective multidimensional data analysis based on routine hematological indicators.Frontiers in pediatrics · 2026Article
- Children with severe cerebral palsy during the COVID-19 pandemic: The vulnerable tell us whether our interventions are working.Developmental medicine and child neurology · 2025Article
- Respiratory admissions and impact of COVID-19 lockdowns for children with severe cerebral palsy.Developmental medicine and child neurology · 2025Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
aimTo explore factors contributing to the burden of respiratory admissions in children with severe cerebral palsy (CP) by comparing admissions to a single tertiary paediatric hospital before, during, and after the period of social restrictions implemented to reduce transmission of COVID-19 (lockdown period).
methodFor this observational study, three severe CP cohorts (pre-lockdown, lockdown, post-lockdown) were identified from a state-wide cerebral palsy register and linked to patient-level clinical and demographic data. Medical records were manually searched to identify respiratory hospitalizations. Frequency and details of admissions were compared across the three 2-year periods.
resultsDuring the lockdown period, there were 24 hospitalizations for respiratory illness per 100 children compared to 37 and 47 in the pre-lockdown and post-lockdown periods (p < 0.001). Respiratory viruses (excluding picornaviruses) were detected in only 7% of lockdown admissions compared to 24% pre-lockdown and 30% post-lockdown. Sputum sampling was performed in 34% of admissions with gram-positive bacteria cultured in 6% admissions and gram-negative bacteria only in 18%.
interpretationThe study findings highlight an important dynamic contribution of viral infections to respiratory illnesses in children with severe CP and the potential to improve outcomes with personalized approaches based on defining individual factors predisposing to recurrent respiratory admissions.
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