Evidence map›Paper›PMID 40344387›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Mercaptophenylboronic Acid-Mediated Nanozyme Immunochromatographic Assay for Simultaneous Detection of Respiratory Bacteria and Virus.

Qing Yu, Jiaxuan Li, Shuai Zheng, Yajin Hu, Benshun Tian, Meirou Lu, Bing Gu, Chongwen Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Peroxidase-Mimicking Nanozymes for Rapid Detection of Infectious Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing YuDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510006, China.
Jiaxuan LiDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510006, China.
Shuai ZhengHefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230036, China.
Yajin HuSchool of Medicine, South China University of Technology, Guangzhou, Guangdong, 510000, China.
Benshun TianSchool of Medicine, South China University of Technology, Guangzhou, Guangdong, 510000, China.
Meirou LuDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510006, China.
Bing GuDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510006, China.
Chongwen WangDepartment of Clinical Laboratory Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510006, China.ORCID https://orcid.org/0000-0002-9627-107X

Funding

National Key Research and Development Program of China 2023YFC2606200National Natural Science Foundation of China 32200076National Natural Science Foundation of China 82272423National Natural Science Foundation of China 82372348Natural Science Fund of Guangdong Province for Distinguished Young Scholars 2025B1515020071Research Foundation for Advanced Talents of Guangdong Provincial People's Hospital KJ012021097
6 · The paper itself

Abstract

Rapid, sensitive, and accurate detection of respiratory pathogens is essential yet challenging. Here, this study presents a universal nanozyme immunochromatographic assay (ICA) that utilizes the broad binding capacity of 4-mercaptophenylboronic acid (MPBA) for glycosylated molecules on bacterial and viral surfaces, along with the colorimetric-catalytic dual enhancement capability of multi-tentacle magnetic nanozyme (FeAu@AuIr), to achieve ultrasensitive, wide-range, and simultaneous detection of multiple respiratory pathogens. The virus-like biomimetic FeAu@AuIr with multi-tentacle shell is prepared by sequentially assembling a layer of large Au nanoparticles and a layer of highly catalytic 5 nm AuIr nanoparticles on 160 nm Fe

Indexed as

Boronic AcidsChromatography, AffinitySARS-CoV-2Sulfhydryl CompoundsColorimetryCOVID-19GoldHumansImmunoassayMetal NanoparticlesPseudomonas aeruginosaStreptococcus pneumoniae4-mercaptophenylboronic acidBoronic AcidsGoldSulfhydryl Compounds4‐mercaptophenylboronic acidbiomimetic magnetic nanozymeimmunochromatographic assayrespiratory pathogensuniversal detection

Identifiers

PMID40344387
PMCPMC12376685

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.