SynthesisPsycho-oncology2025
Effects of Web-Based Interventions on Anxiety and Depression in Patients With Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Synthesis in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Clinically Meaningful, Patient-Centered Endpoints for Real-World Evidence Generation in Breast Cancer: Perspectives from the Multidisciplinary TRIUMPH Initiative.Advances in therapy · 2026Article
- Article
- Scoping review of psychosocial support interventions in oncology nursing: Applications across diverse and underserved cancer populations.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study evaluated the effects of web-based interventions on anxiety and depression in patients with breast cancer by conducting a meta-analysis of relevant randomized controlled trials (RCTs).
methodsWe searched the PubMed, Web of Science, Cochrane Library, Cumulated Index to Nursing and Allied Health Literature, Embase, and PsycINFO databases from their inception to January 5, 2024. When substantial heterogeneity was observed among the studies, a random-effects model was applied to calculate effect sizes in terms of the standardized mean difference (SMD) and assessed the quality of the included studies using the updated Cochrane risk-of-bias tool for RCTs.
resultsFourteen RCTs were included in this study. The meta-analysis indicated that web-based intervention alleviated anxiety (SMD = -0.26, 95% CI = -0.44 to -0.07, p < 0.01, I
conclusionsThis study showed that web-based interventions may help reduce anxiety and depression in patients with breast cancer. It also suggested the potential of these interventions as a strategy for alleviating symptoms in non-face-to-face settings. However, the limited number of studies and high heterogeneity in the subgroup analysis made it difficult to assess the effects of different intervention methods. Further high-quality research is needed to provide more reliable data on the effectiveness of various intervention methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.