Evidence map›Paper›PMID 40344188›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Clustering Patients with Pulmonary Hypertension Using the Plasma Proteome.

Athénaïs Boucly, Shanshan Song, Merve Keles, Dennis Wang, Luke S Howard, Marc Humbert, Olivier Sitbon, Allan Lawrie, A A Roger Thompson, Philipp Frank and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07653958 (Research on the Clinical Risk Factor Assessment System for Acute Pulmonary Hypertension Crisis and Its Mortality), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07653958 recruitingnot on this mapstarted 2026, after this paper: background citation

Research on the Clinical Risk Factor Assessment System for Acute Pulmonary Hypertension Crisis and Its Mortality

TypeobservationalSponsorPeking Union Medical College HospitalRan2026 to 2029Enrolled5,000ConditionsPulmonary Hypertension, Pulmonary Hypertension Crisis
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. A Peek into Pulmonary Hypertension through the Plasma Proteome.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Athénaïs BouclyNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0001-6246-5557
Shanshan SongNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0002-0851-8387
Merve KelesNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0002-5212-3753
Dennis WangNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-0068-1005
Luke S HowardNational Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom.ORCID 0000-0003-2822-210X
Marc HumbertUniversité Paris-Saclay, INSERM UMR_S 999 (HPPIT), Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.ORCID 0000-0003-0703-2892
Olivier SitbonUniversité Paris-Saclay, INSERM UMR_S 999 (HPPIT), Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.ORCID 0000-0002-1942-1951
Allan LawrieNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-4192-9505
A A Roger ThompsonDivision of Clinical Medicine, The University of Sheffield, Sheffield, United Kingdom.ORCID 0000-0002-0717-4551
Philipp FrankBrain Sciences, University College London, London, United Kingdom; and.
Mika KivimakiBrain Sciences, University College London, London, United Kingdom; and.ORCID 0000-0002-4699-5627
Christopher J RhodesNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0002-4962-3204
Martin R WilkinsNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-3926-1171

Funding

ERS/EU Respire 4 Marie Skłodowska-Curie Postdoctoral Research Fellowship R4202205-00947
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood ProteinsHypertension, PulmonaryProteomeAdultAgedBiomarkersCase-Control StudiesCluster AnalysisFemaleFranceHumansMaleMiddle AgedProteomicsUnited KingdomBiomarkersBlood ProteinsProteomeclassificationproteomicspulmonary hypertensiontheragnostics

Identifiers

PMID40344188
PMCPMC12369885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.