Evidence map›Paper›PMID 40344064›Full record

ArticleScience advances2025

Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense.

Wen-Hao Han, Feng-Bin Zhang, Shun-Xia Ji, Kai-Lu Liang, Jun-Xia Wang, Xiao-Ping Fan, Shu-Sheng Liu, Xiao-Wei Wang

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wen-Hao HanState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0008-0219-9507
Feng-Bin ZhangState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-4041-8770
Shun-Xia JiState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0002-5284-6190
Kai-Lu LiangState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.
Jun-Xia WangState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.
Xiao-Ping FanLC-Bio Technology Co. Ltd., Hangzhou 310018, China.ORCID 0009-0002-9929-6296
Shu-Sheng LiuState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-7711-6405
Xiao-Wei WangState Key Laboratory of Rice Biology and Breeding, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-7472-3944

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the plant vigor hypothesis, younger, more vigorous plants tend to be more susceptible to herbivores compared to older, mature plants, yet the molecular mechanisms underlying this dynamic remain elusive. Here, we uncover a hormonal cross-talk framework that orchestrates the age-related balance between plant growth and herbivore defense. We demonstrate that the accumulation of salicylic acid (SA), synthesized by

Indexed as

HerbivoryIndoleacetic AcidsNicotianaPlant DevelopmentSalicylic AcidAnimalsGene Expression Regulation, PlantMicroRNAsPhenylalanine Ammonia-LyasePlant ProteinsSignal TransductionIndoleacetic AcidsMicroRNAsPhenylalanine Ammonia-LyasePlant ProteinsSalicylic Acid

Identifiers

PMID40344064
PMCPMC12063664

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.