Evidence map›Paper›PMID 40343935›Full record

SynthesisPloS one2025

Active trachoma among children aged 1-9 years in Ethiopia: A meta-analysis from 2019 to 2024.

Kibruyisfaw Weldeab Abore, Melat Tesfaye Asebot, Gifty Berhanemeskel Kebede, Robel Tibebu Kasaye, Asonya Abera Akuma, Mahlet Minwuyelet Dagne, Tewobesta Fesseha Tesfaye, Mahlet Tesfaye Abebe, Estifanos Bekele Fole

Abstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kibruyisfaw Weldeab AboreDepartment of Ophthalmology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-0002-0581
Melat Tesfaye AsebotBloomberg School of Public Health, John Hopkins University, Baltimore, Maryland, United States of America.
Gifty Berhanemeskel KebedeDepartment of Ophthalmology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Robel Tibebu KasayeDepartment of Ophthalmology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0004-4093-5908
Asonya Abera AkumaCollege of Medicine and Health Sciences, Arbaminch University, Arbaminch, Ethiopia.ORCID https://orcid.org/0009-0002-9240-6413
Mahlet Minwuyelet DagneSt. Peter's Specialized Hospital, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0004-9661-584X
Tewobesta Fesseha TesfayeMinistry of Health Ethiopia, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0004-8979-8393
Mahlet Tesfaye AbebeDepartment of Medicine, Yirgalem Hospital Medical College, Yirgalem, Ethiopia.
Estifanos Bekele FoleDepartment of Medicine, Yirgalem Hospital Medical College, Yirgalem, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrachoma is a leading infectious cause of blindness and of significant public health concern targeted for elimination. This study aimed to systematically summarize the magnitude of active trachoma among children aged 1-9 in Ethiopia from 2019-2024.

methodsThe review was prospectively registered on PROSPERO (Registration number: CRD42024514026). Database searches were conducted on Google Scholar, SCOPUS, PubMed, EMBASE, and Africans Journals Online (AJOL) for studies published between January 2019-31-March-2024 and with restriction to articles published only in English. Data extraction was done using a pre-prepared Excel sheet. STATA version 17 was used to perform the analysis. Heterogeneity between studies was assessed using I2 statistics and Cochrane Q. Qualitative synthesis was done to summarize the studies and random effect model was used to estimate the Pooled magnitude of active trachoma with a corresponding 95% confidence interval.

resultsA total of 17 studies with 19793 subjects were included in the meta-analysis. The pooled magnitude of active trachoma among children aged 1-9 years was found to be 18.4% (95% CI: 13.88, 22.91). We found a statistically significant heterogeneity between studies. Among the regions, Southwest region was found to have the highest magnitude (44.1%) (95%CI: 41.8%, 46.4%) and Dire Dawa was found to have the lowest (4.3%) (95%CI: 2.9%, 5.7%).

conclusionThe magnitude of active trachoma is still higher than the World Health Organization (WHO) target for elimination. There was significant interregional difference in magnitude of active trachoma. Strengthening surgical treatment for trichiasis, antibiotic therapy, facial hygiene, and environmental improvement (SAFE) strategy and health education and promotion is recommended.

Indexed as

TrachomaChildChild, PreschoolEthiopiaFemaleHumansInfantMale

Identifiers

PMID40343935
PMCPMC12063883

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.