Evidence map›Paper›PMID 40343888›Full record

ArticlePloS one2025

Climacteric women's perspectives on menopause and hormone therapy: Knowledge gaps, fears, and the role of healthcare advice.

Marcio Alexandre H Rodrigues, Zilma Silveira Nogueira Reis, Ana Paula de Andrade Verona, Matheus Candido Teixeira, Gisele Lobo Pappa, Jose Maria Soares Junior, Agnaldo Lopes da Silva Filho, Edmund Chada Baracat, Gustavo Arantes Rosa Maciel

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Menopausal hormone therapy in Türkiye: physician knowledge and practice gaps.Revista da Associacao Medica Brasileira (1992) · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcio Alexandre H RodriguesObstetrics and Gynecology Department, School of Medicine, UFMG, Av. Alfredo Balena,190-2 andar, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-0969-4614
Zilma Silveira Nogueira ReisObstetrics and Gynecology Department, School of Medicine, UFMG, Av. Alfredo Balena,190-2 andar, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0001-6374-9295
Ana Paula de Andrade VeronaDepartment of Demography, Cedeplar, UFMG, Pres. Antônio Carlos, Belo Horizonte, Minas Gerais, Brazil.
Matheus Candido TeixeiraFederal Institute of Mato Grosso, Avenida Sen. Filinto Müller, 953, Cuiaba, Montana, Brazil.ORCID 0000-0003-1103-5383
Gisele Lobo PappaComputer Science Department, UFMG, Rua Reitor Píres Albuquerque, ICEx -Belo Horizonte, Minas Gerais, Brazil.
Jose Maria Soares JuniorDisciplina de Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR. Av. Dr. Eneas, Carvalho de Aguiar, 255, andar, São Paulo, Brazil.ORCID 0000-0003-0774-9404
Agnaldo Lopes da Silva FilhoObstetrics and Gynecology Department, School of Medicine, UFMG, Av. Alfredo Balena,190-2 andar, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-8486-7861
Edmund Chada BaracatDisciplina de Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR. Av. Dr. Eneas, Carvalho de Aguiar, 255, andar, São Paulo, Brazil.ORCID 0000-0003-0111-9030
Gustavo Arantes Rosa MacielDisciplina de Ginecologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR. Av. Dr. Eneas, Carvalho de Aguiar, 255, andar, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to evaluate the knowledge, attitudes, and practices of Brazilian women regarding menopause, related symptoms, and the use of hormone therapy, including indications and contraindications.

methodsA cross-sectional study was conducted between 2022/07/18 and 2023/10/01, involving women aged 40-65 years from various cities in Minas Gerais, São Paulo, and other regions of Brazil. A structured KAP (Knowledge, Attitudes, and Practices) Survey was used to assess sociodemographic characteristics, the prevalence of menopausal symptoms, and the participants' knowledge and practices concerning Menopause Hormone Therapy (MHT).

resultsThe median age of the women surveyed was 50 years; 55.4% were postmenopausal (median age 55), and 44.6% were premenopausal (median age 45). The data indicate limited knowledge about menopause among Brazilian women. Less than one-third (30.3%) expressed satisfaction with the information they had received regarding menopause and available treatment options. Furthermore, 92.97% of participants demonstrated little or no knowledge of hormone therapy. Nearly 27% were unaware of MHT, and 22% opposed its use. Only 29% reported current use of MHT, with common reasons for discontinuation including fear of side effects and contraindications advised by gynecologists.

conclusionThe findings indicate that many Brazilian women have insufficient knowledge about menopause and hormone therapy. Furthermore, a lack of information and training among healthcare providers may lead to the low utilization of menopausal hormone therapy (MHT). To effectively address menopausal symptoms and empower women to make informed choices about hormone therapy, it is crucial to improve access to accurate information and enhance the training of healthcare providers.

Indexed as

Estrogen Replacement TherapyHealth Knowledge, Attitudes, PracticeHormone Replacement TherapyMenopauseAdultAgedBrazilCross-Sectional StudiesFearFemaleHumansMiddle AgedSurveys and Questionnaires

Identifiers

PMID40343888
PMCPMC12063881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.