Evidence map›Paper›PMID 40343605›Full record

ArticleInternational ophthalmology2025

MiR-6837-3p protected retinal epithelial cells from oxidative stress by targeting E2F6.

Xin Zhao, Xinru Chen, Xiangyang Xin

Abstract read
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In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xin Zhao *Department of Ophthalmology, Baogang Hospital of Inner Mongolia, Baotou, 014010, Inner Mongolia, China.
Xinru Chen *Department of Ophthalmology, Baogang Hospital of Inner Mongolia, Baotou, 014010, Inner Mongolia, China.
Xiangyang XinDepartment of Ophthalmology, Baotou Central Hospital, Baotou, 014040, Inner Mongolia, China. xinxiangyang_2006@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe mechanism of age-related macular degeneration (AMD) is a complex illness that is not fully understood. Therefore, the aim of this study was to investigate the expression patterns of miR-6837-3p in retinal epithelial cells.

methodsH

resultsH

conclusionsThe MiR-6837-3p/E2F6 axis might be a target for the treatment of AMD to improve ARPE-19 cell function.

Indexed as

Gene Expression RegulationMacular DegenerationMicroRNAsOxidative StressRetinal Pigment EpitheliumApoptosisCell LineCell MovementCell ProliferationCells, CulturedCell SurvivalFlow CytometryHumansHydrogen PeroxideReactive Oxygen SpeciesHydrogen PeroxideMicroRNAsReactive Oxygen SpeciesAge-related macular degenerationApoptosisARPE-19Cell cycleE2F6MiR-6837-3p

Identifiers

PMID40343605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.