Evidence map›Paper›PMID 40343546›Full record

ArticleInternational ophthalmology2025

Fundus fluorescein angiography findings in eyes initially diagnosed with idiopathic epiretinal membrane.

Chen Chen, Qi Zhang, Linrui Li, Xiaoyan Ding, Lin Lu, Xiujuan Zhao

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chen Chen *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China.
Qi Zhang *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China.
Linrui Li *Department of Ophthalmology, Fushun People's Hospital, Fushun, 643200, China.
Xiaoyan DingState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China.
Lin LuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China. drlulin@126.com.
Xiujuan ZhaoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China. zhaoxiujuan@gzzoc.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to investigate the fundus fluorescein angiography (FFA) findings in eyes initially diagnosed with idiopathic epiretinal membrane (iERM) and assess their impact on best-corrected visual acuity (BCVA).

methodsThis retrospective comparative study included 136 patients (151 eyes) diagnosed with iERM and a control group of 121 healthy fellow eyes. All patients underwent FFA and optical coherence tomography (OCT). The primary outcomes summarized the characteristics of FFA and OCT in patients with iERM, and analyzed the relationship between FFA findings and visual acuity.

resultsVascular leakage (P = 0.009) were significantly more prevalent in eyes with iERM compared to controls. Multivariate logistic regression analysis indicated that optic disc hyperfluorescence (OR 4.05; 95% CI 1.79-9.17; P = 0.001) were more likely to present in eyes with iERM. A lower OCT stage, fovea-recognizable, cellophane macular reflex type were associated with better BCVA.

conclusionOptic disc hyperfluorescence is independent risk factors of iERM. Howerer, these abnormalities do not show a significant association with visual function. The precise etiology remains to be fully elucidated.

Indexed as

Epiretinal MembraneFluorescein AngiographyVisual AcuityAdultAgedFemaleFundus OculiHumansMaleMiddle AgedOptic DiskRetrospective StudiesTomography, Optical CoherenceBest-corrected visual acuityEpiretinal membraneFluorescein angiographyOptical coherence tomography

Identifiers

PMID40343546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.