Trial reportSurgical endoscopy2025
The association between the cutaneous sensory block area, the surgical incision's location, and the block's analgesic efficacy: a post hoc sensitivity analysis of data from a controlled randomised multicentre trial.
Trial report in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Surgeon-guided transversalis fascia plane block vs. trocar site wound infiltration in pediatric laparoscopic appendectomy.Irish journal of medical science · 2025Trial
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundTransversus abdominis plane blocks are widely used, but the association between the cutaneous sensory block area and the analgesic effect is still debated. We aimed to determine the relationship between the cutaneous sensory block area, the surgical incision's location, and the block's analgesic efficacy.
methodsA sensitivity analysis of data from a multicentre, patient-, clinician-, investigator-blinded, placebo- and active-controlled, 3-arm randomised clinical trial. Patients undergoing minimally invasive colon surgery were included from four hospitals across Denmark between January 2021 and February 2024. In this sensitivity analysis, we used our previously collected data of the cutaneous sensory block area to examine the efficacy of two different approaches to the transversus abdominis plane block, as compared to each other and placebo based on incision location. The primary outcome was total morphine dose equivalents administered in the first 24 h after minimally invasive surgery in patients receiving either a Pfannenstiel or a supraumbilical transverse incision.
resultsWe found that the subcostal dual laparoscopic-assisted transversus abdominis plane block was superior to both the ultrasound-guided posterior transversus abdominis plane block and placebo in patients with a Pfannenstiel incision with an absolute difference of - 8.9 mg (95% CI, - 16.5 to - 1.3 mg; p = 0.02) and - 10.3 mg (95% CI, - 17.0 to - 3.6 mg; p < 0.01) morphine dose equivalents, respectively. No difference was found for the supraumbilical transverse incision. Patient-reported outcome measures favoured the laparoscopic-assisted block, with an absolute difference of 13 (95% CI, 1.7-24.3; p = 0.025) in the Quality of Recovery-15 score compared to placebo.
conclusionThe effect of the transversus abdominis plane block seems to be independent of the distribution of the cutaneous sensory block area of the approach. The laparoscopic-assisted subcostal transversus abdominis plane block reduced postoperative pain with a high QoR-15 score.
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