Evidence map›Paper›PMID 40343513›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2025

Well-being and biological cost of family members affected by substance use disorder of others.

Zhao-Rong Chen, Nian-Nian Zhang, Wen-Yu Cao, Qian Liu, Yan-Hui Cui, Xiao-Yu Lu, Jia-Yu Yao, Fang Li, Chang-Qi Li

Abstract read
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In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhao-Rong Chen *Department of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China.
Nian-Nian Zhang *Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, People's Republic of China.
Wen-Yu CaoClinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan Province, 421001, People's Republic of China.
Qian LiuLituo Drug Rehabilitation Institute of Hunan Province, Changsha, Hunan Province, 410000, People's Republic of China.
Yan-Hui CuiDepartment of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China.
Xiao-Yu LuDepartment of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China.
Jia-Yu YaoDepartment of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China.
Fang LiDepartment of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China. fangli@csu.edu.cn.
Chang-Qi LiDepartment of Anatomy and Neurobiology, Xiangya School of Basic Medical Science, Central South University, Changsha, Hunan Province, 410013, People's Republic of China. changqili@csu.edu.cn.

Funding

National Natural Science Foundation of China 32371210Natural Science Foundation of Hunan Province 2023JJ30724
6 · The paper itself

Abstract

This cross-sectional study assessed the well-being of family members affected (AFMs) by substance use disorder (SUD) of other family members. Mental symptoms, social avoidance, and quality of life (QoL) were measured for 775 Chinese AFMs and 206 controls. Saliva from 65 AFMs and 31 controls was analyzed for cortisol, BDNF, proBDNF, and mRNA levels of BDNF and its receptors (TrkB, P75

Indexed as

Adaptation, PsychologicalCost of IllnessFamilyQuality of LifeSocial SupportSubstance-Related DisordersAdultBrain-Derived Neurotrophic FactorChinaCross-Sectional StudiesFemaleHumansHydrocortisoneMaleMiddle AgedYoung AdultBDNF protein, humanBrain-Derived Neurotrophic FactorHydrocortisoneAffected family membersBDNFCortisolMental healthQuality of lifeSocial avoidanceSubstance use disorder

Identifiers

PMID40343513

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.