ArticleCroatian medical journal2025
Aeroallergen sensitization rate and its multifactorial influences in continental Croatia: a cross-sectional study.
Article in Croatian medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimsTo assess the rate of sensitization to airborne allergens in continental Croatia and the related variables. A secondary aim was to assess the frequency of pollen-food syndrome.
methodsThis cross-sectional study enrolled 2133 participants referred to Special Hospital for Pulmonary Diseases, Zagreb, from January 2 to December 31, 2022. Patients underwent skin prick test, and data on age, area of residence, smoking status, referring physician, and the presence of respiratory disease were gathered from electronic health records.
resultsThe rate of sensitization in our sample was 48.86%, and rate of polysensitization was 75.91%, with grass pollen being the predominant allergen. Sensitization rates to all airborne allergens significantly increased compared with a 2003-2006 cohort. Men had higher rates of sensitization, and sensitivity to certain allergens varied based on age. Patients diagnosed with rhinitis exhibited the highest rates of sensitization and mostly sought medical attention from allergists. Conversely, asthma patients who did not have rhinitis exhibited reduced rates of sensitization and were mostly treated by pulmonologists. Birch tree pollen was the primary aeroallergen responsible for pollen-food syndrome, regardless of the age group.
conclusionsOur findings contribute to the existing body of research on sensitization to aeroallergens in Europe and stress the importance of multidisciplinary management of allergic respiratory disorders.
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40343431PMC12093119What OpenQuestion holds
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