Evidence map›Paper›PMID 40343417›Full record

ArticleZoological research2025

Single-cell sequencing reveals alterations in the ovarian immune microenvironment regulated by 17β-estradiol in neonatal mice.

Yu-Tong Yan, Yan-Xue Li, Yi-Ting Meng, Qian Li, Xiao-E Zhao, Qiang Wei, Meng-Hao Pan, Sha Peng, Bao-Hua Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu-Tong YanCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Yan-Xue LiCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Yi-Ting MengCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Qian LiCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Xiao-E ZhaoCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Qiang WeiCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Meng-Hao PanCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Sha PengCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.
Bao-Hua MaCollege of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immunomodulatory function of estrogen within the ovary remains a subject of ongoing debate, and the neonatal ovarian immune microenvironment, particularly its modulation by estrogen, has not been comprehensively characterized. In this study, the effects of 17β-estradiol (E

Indexed as

EstradiolOvaryAnimalsAnimals, NewbornFemaleGene Expression RegulationMacrophagesMiceMice, Inbred C57BLSingle-Cell AnalysisEstradiol17β-estradiolImmune cellsImmune microenvironmentOvaryTranscriptional alterations

Identifiers

PMID40343417
PMCPMC12361894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.