Evidence map›Paper›PMID 40343405›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2025

Neutrophil-To-Lymphocyte Ratio and Delivery Within 24 h in Preterm Premature Rupture of Membranes: A Retrospective Cohort Study.

Daniel Gabbai, Itamar Gilboa, Anat Lavie, Yariv Yogev, Emmanuel Attali

Abstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Neutrophil-to-lymphocyte ratio at admission helps to predict the need for blood transfusion after vaginal delivery.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel GabbaiLis Hospital for Women's Health, Tel Aviv Sourasky Medical Centre, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0001-7290-3477
Itamar GilboaLis Hospital for Women's Health, Tel Aviv Sourasky Medical Centre, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-0941-2074
Anat LavieLis Hospital for Women's Health, Tel Aviv Sourasky Medical Centre, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yariv YogevLis Hospital for Women's Health, Tel Aviv Sourasky Medical Centre, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Emmanuel AttaliLis Hospital for Women's Health, Tel Aviv Sourasky Medical Centre, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association between maternal neutrophil-to-lymphocyte ratio (NLR) and delivery within 24 h in women with preterm premature rupture of membranes (PPROM). STUDY DESIGN AND

settingRetrospective cohort study in a single university-affiliated tertiary medical centre. POPULATION: Women with PPROM at ≤ 36 + 6 weeks' gestation planning vaginal delivery. Exclusions included women who lacked complete blood count (CBC) data within the first 24 h from PPROM caesarean delivery.

methodsMaternal demographic and clinical data, including age, gestational age, body mass index, parity and mode of conception, were collected. Women who delivered within 24 h of membrane rupture were compared to those who did not via univariate and multivariate Cox analyses.

main outcome measureWomen who delivered within 24 h from rupture of membrane.

resultsAmong 145 833 deliveries during the study period, 1498 women (0.9%) presented with PPROM. After exclusions, 371 women were included, with 173 (46.6%) delivering spontaneously within 24 h. Cox regression analysis identified NLR > 10 (HR = 1.60; 95% CI, 1.06-2.40; p = 0.025) as an independent risk factor for spontaneous delivery within 24 h.

conclusionElevated maternal NLR is associated with delivery within 24 h in PPROM and may support clinical assessment for anticipating imminent preterm delivery, aiding in management decisions for this population.

Indexed as

LymphocytesNeutrophilsPremature BirthPremature Rupture of Fetal MembranesAdultDelivery, ObstetricFemaleGestational AgeHumansLymphocyte CountPregnancyProportional Hazards ModelsRetrospective StudiesRisk FactorsTime FactorsdeliveryNLRPPROMrisk factors

Identifiers

PMID40343405
PMCPMC12315057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.