Evidence map›Paper›PMID 40343365›Full record

ArticleFrontiers in veterinary science2025

Transcriptomic signatures in response to antioxidants supplementation in Korean cattle beef,

Kangwook Lee, La Yoon Choi, Jun Sang Ahn, Jae Yong Song, Joong Kook Park, Suk Jun Yun, Jeong Heon Lee, Eui-Cheol Shin, Soo-Jin Yeom, Jiangchao Zhao and 9 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Kangwook LeeDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
La Yoon ChoiDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
Jun Sang AhnNonghyup Feed, Seoul, Republic of Korea.
Jae Yong SongNonghyup Feed, Seoul, Republic of Korea.
Joong Kook ParkNonghyup Feed, Seoul, Republic of Korea.
Suk Jun YunNonghyup Feed, Seoul, Republic of Korea.
Jeong Heon LeeNonghyup Feed, Seoul, Republic of Korea.
Eui-Cheol ShinDepartment of GreenBio Science, Gyeongsang National University, Jinju, Republic of Korea.
Soo-Jin YeomSchool of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea.
Jiangchao ZhaoDepartment of Animal Science, Dale Bumpers College of Agricultural, Food and Life Sciences, University of Arkansas, Fayetteville, AR, United States.
Tae Jin ChoDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
Nam Su OhDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
Jeong-Oh ShinDepartment of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea.
Dahye KimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Tae Gyun KimThe Bioinformatix, Gwangmyeong, Republic of Korea.
Hyung Taek ChoThe Bioinformatix, Gwangmyeong, Republic of Korea.
Hyo Ri ShinDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
Young Jun KimDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.
Jae Kyeom KimDepartment of Food and Biotechnology, Korea University, Sejong, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The present study investigated the effects of antioxidant supplementation on the transcriptomic profiles of Methods: Twelve castrated Results and discussion: While no significant differences were observed in phenotypic traits such as weight gain and feed conversion ratio, transcriptomic analysis identified 641 differentially expressed genes between the CON and FEED groups. Functional enrichment analysis revealed that differentially expressed genes were mainly associated with transcription regulation, pseudouridine synthesis, and mitochondrial function. These findings suggest that antioxidant supplementation elicits significant molecular changes in the liver, particularly affecting transcriptional activity and mitochondrial processes, even in the absence of detectable phenotypic differences.

Indexed as

antioxidant supplementationHanwoo cattlemitochondrial functionRNA sequencingtranscriptomics

Identifiers

PMID40343365
PMCPMC12061023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.