Evidence map›Paper›PMID 40343327›Full record

ArticleCurrent behavioral neuroscience reports2025

Noninvasive Brain Stimulation for Opioid Use Disorder: An Update of the Literature.

Sophia H Blyth, Carri Polick, Lena Kim, Sonya Eason, Dana Rubenstein, Suzanna Thompson, Trevor Drummond, Heather Burrell Ward, Jonathan R Young

Abstract read
In one paragraph

Article in Current behavioral neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sophia H BlythDepartment of Psychiatry and Behavioral Science, Vanderbilt University Medical Center, Nashville, TN.
Carri PolickDuke University School of Nursing, Durham, NC.
Lena KimDepartment of Psychiatry and Behavioral Science, Vanderbilt University Medical Center, Nashville, TN.
Sonya EasonDepartment of Statistical Science, Duke University Trinity College of Arts and Sciences, Durham, NC.
Dana RubensteinDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.
Suzanna ThompsonSocial Science Research Institute, Duke University, Durham, NC.
Trevor DrummondDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.
Heather Burrell WardDepartment of Psychiatry and Behavioral Science, Vanderbilt University Medical Center, Nashville, TN.
Jonathan R YoungDurham VA Health Care System, Durham, NC.

Funding

NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Network-Targeted Neuromodulation for Nicotine Dependence in SchizophreniaK23DA059690 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Heather Burrell Ward · 2024 to 2026
$557k
CSRD VA IK2 CX002610NCATS NIH HHS TL1 TR002555NIDA NIH HHS K23 DA059690
6 · The paper itself

Abstract

Purpose of review: Although medications for opioid use disorder (OUD) are effective, relapse remains common. Noninvasive brain stimulation (NIBS) has emerged as a potential adjunctive treatment. We review publications since 2020 that tested NIBS interventions in humans and assessed clinically relevant outcomes. Recent findings: We identified a total of 19 studies of NIBS for treatment of craving; acute detoxification, withdrawal, and early abstinence; relapse prevention; cognitive dysfunction associated with OUD; mood and anxiety symptoms in OUD; co-occurring SUDs with OUD; and post-operative pain management and prevention of OUD. Summary: NIBS interventions, particularly repetitive transcranial magnetic stimulation and transcranial direct current stimulation have demonstrated preliminary evidence of effectiveness to treat OUD and its associated symptoms.

Indexed as

noninvasive brain stimulation (NIBS)opioid use disorder (OUD)repetitive transcranial magnetic stimulation (rTMS)transcranial alternating current stimulation (tACS)transcranial direct current stimulation (tDCS)vagus nerve stimulation (VNS)

Identifiers

PMID40343327
PMCPMC12058202

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.