ArticleRSC advances2025
Iodine-mediated synthesis of indolyl-1,3,4-thiadiazole amine derivatives and their DFT analysis.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Iodine/TBAB-promoted oxidative cyclization: an efficient approach to thiadiazoles.RSC advances · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An effective iodine-mediated one-pot three-component strategy for the construction of indolyl-1,3,4-thiadiazole amines has been described. The method involved the reaction of tosylhydrazine with indole-3-carboxaldehyde and ammonium thiocyanate as a non-toxic source of sulphur under metal-free conditions. The developed protocol included readily available substrates, shorter reaction time, use of low-toxic thiocyanate, and benzylation with a broad substrate scope, making it a viable approach for multiple applications. Furthermore, DFT analysis was conducted using the Gaussian 09 package.
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Registered trials
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