Evidence map›Paper›PMID 40342911›Full record

ArticleFood chemistry: X2025

Integrated widely targeted metabolomics and flavoromics reveal processing-driven dynamic changes in functional metabolites of

Yiyun Lin, Hui Ouyang, Ruobing Li, Yunzhe Shao, Xiangrong Tian, Yongkang Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Phytochemical-richFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiyun LinNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.
Hui OuyangNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.
Ruobing LiNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.
Yunzhe ShaoNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.
Xiangrong TianNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.
Yongkang ZhangNational & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study employed a widely targeted metabolomics approach combined with flavoromics evaluation to systematically analyze dynamic metabolic variations under four processing techniques: fresh EUL (XY), traditionally dried EUL (HG), green tea processed EUL (GT), and black tea processed EUL (BT). A total of 1839 non-volatile metabolites and 289 volatile metabolites were identified. Key affected metabolites included amino acids (e.g., essential amino acids upregulated 90 % in HG), lipids (oxidized fatty acids elevated in BT), phenolic acids (23 % increase in GT), flavonoids (120+ downregulated in BT), nucleotides, and terpenoids. Each processing method demonstrates unique advantages: HG preserves amino acids, GT enhances catechin content, and BT optimizes secondary metabolites. This study provides the first comprehensive metabolic map of EUL processing, offering a scientific foundation for standardizing product quality and developing functional applications.

Indexed as

Eucommia ulmoides leavesFlavoromics evaluationFunctional metabolitesprocessing methodTeaWidely targeted metabolomics

Identifiers

PMID40342911
PMCPMC12059405

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.